ID   A0A2K1QJH1_9PEZI        Unreviewed;       853 AA.
AC   A0A2K1QJH1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=HBS1-like protein {ECO:0000313|EMBL:PNS15003.1};
GN   ORFNames=CAC42_2232 {ECO:0000313|EMBL:PNS15003.1};
OS   Sphaceloma murrayae.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Myriangiales; Elsinoaceae; Sphaceloma.
OX   NCBI_TaxID=2082308 {ECO:0000313|EMBL:PNS15003.1, ECO:0000313|Proteomes:UP000243797};
RN   [1] {ECO:0000313|EMBL:PNS15003.1, ECO:0000313|Proteomes:UP000243797}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CQ-2017a {ECO:0000313|EMBL:PNS15003.1,
RC   ECO:0000313|Proteomes:UP000243797};
RA   Cheng Q.;
RT   "Draft genome sequence of a variant of Elsinoe murrayae.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PNS15003.1}.
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DR   EMBL; NKHZ01000081; PNS15003.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2K1QJH1; -.
DR   STRING; 2082308.A0A2K1QJH1; -.
DR   InParanoid; A0A2K1QJH1; -.
DR   OrthoDB; 5477300at2759; -.
DR   Proteomes; UP000243797; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   CDD; cd01883; EF1_alpha; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 2.
DR   InterPro; IPR015033; HBS1-like_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR   PANTHER; PTHR23115:SF309; ELONGATION FACTOR EF-1 SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04630)-RELATED; 1.
DR   PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF03143; GTP_EFTU_D3; 1.
DR   Pfam; PF08938; HBS1_N; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50447; Translation proteins; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   4: Predicted;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000243797};
KW   Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT   DOMAIN          427..650
FT                   /note="Tr-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51722"
FT   REGION          1..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          91..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          243..288
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          369..411
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..39
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        372..395
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   853 AA;  93181 MW;  0CEB183AFF5AA6B8 CRC64;
     MSGHRRVKNV DYDDADDYDD YDDDVQEVDG PTGGDDELTE EDREQLRIGT AKVRSIIQES
     SHISNRTIED ALWHYYYDIE KTVVYLKNEH QPTTPKAKKP SRFDQAAAAS AEKNPVPSSA
     GKSYSLSTDH LGRDHAWKHV VATTEYPAPA RANTELRGGT GAQPRFDVFA GITWSAPTPE
     TRCVFTPIER RPRLRLLGGS GKPSKLAALA AARKKEKENQ ASGERVSGAL SLLDRLNSKD
     MALKEPTATP LKVDKAEPMP VPPEKRTISS LATRSKRPSV PSAPAEPVKA QQLPIFEPPK
     KALPTVEQLS SGPSSFGWML SALSQSSADP LSPERFQHNL TLALLRTLDV PSQESFRGPS
     PDAVVLRAQA KGKTTGQPSQ SSKETRDTKQ VTKAVGNLSV APPPPPPVRI KSKNLNVPFE
     YANAKPRKEL NFVVVGHIDH GKSTLMGRLL YEHNVIDARS LEKFRKEAAK LGKESFHLAW
     VMDAREDERE HGVTIDYAEK NFSTASTDFT IIDAPGHRDY VGNMIAGTAM ADFALLVVDA
     GANSFAAGLK GQTREHAQIV RSHKLEKIIV VVNKMDSVSW SKDAFNSVMD QTTSFLAEQL
     FNPADVIFVP VSGLSGENIT ARPGSSNALW YTGPSLVQAL DNIQPKREQY LGKISDPFRL
     RVAGFSGLSE LAEFLPPGSQ APFTVYGRVD AGTCQVGDRL TAQPSGETVV IKVITKGGEP
     RDYAVPGQII GIQLVECDED RLARGDLLCG EPPVRATKKV TMKILAFDVV FPMPVDVHRG
     RMRAYGRVAE LVSRLDRTTH AVVKNKPKII KTGETARVTV EFDESTPLER GERVVLRYAG
     VTVAAGAVEK GEA
//