ID A0A2K1QQY5_9PEZI Unreviewed; 1340 AA.
AC A0A2K1QQY5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Calcium permeable stress-gated cation channel 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CAC42_6966 {ECO:0000313|EMBL:PNS17283.1};
OS Sphaceloma murrayae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Myriangiales; Elsinoaceae; Sphaceloma.
OX NCBI_TaxID=2082308 {ECO:0000313|EMBL:PNS17283.1, ECO:0000313|Proteomes:UP000243797};
RN [1] {ECO:0000313|EMBL:PNS17283.1, ECO:0000313|Proteomes:UP000243797}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CQ-2017a {ECO:0000313|EMBL:PNS17283.1,
RC ECO:0000313|Proteomes:UP000243797};
RA Cheng Q.;
RT "Draft genome sequence of a variant of Elsinoe murrayae.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNS17283.1}.
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DR EMBL; NKHZ01000051; PNS17283.1; -; Genomic_DNA.
DR InParanoid; A0A2K1QQY5; -.
DR OrthoDB; 54187at2759; -.
DR Proteomes; UP000243797; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR022257; PHM7_ext.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR PANTHER; PTHR13018:SF20; SPORULATION-SPECIFIC PROTEIN 75; 1.
DR Pfam; PF14703; PHM7_cyt; 2.
DR Pfam; PF12621; PHM7_ext; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000243797};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 37..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 737..762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 782..806
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 827..847
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 876..904
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 925..944
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 992..1011
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1023..1044
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..188
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 212..296
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 635..723
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 737..1007
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 1239..1331
FT /note="10TM putative phosphate transporter extracellular
FT tail"
FT /evidence="ECO:0000259|Pfam:PF12621"
FT REGION 284..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 341..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1077..1221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..308
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..326
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..500
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1089..1132
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1142..1156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1204..1220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1340 AA; 149715 MW; 0106B1A8EB25BF3E CRC64;
MAEVPAATAT PGAGLGGFLD SGSGRATKSD TQSVGTLVAS ITTAAASFGI QFLVFIILRW
RLTRIYRPKT YLVPERQRVP IPPSGPWQWI APIFTTSNST IISRCGLDAY YFLRFLRMLL
KIFIPMALVI LPILIPINRY SGSQDNRATG VNELGWPNVS PPSIRRLWAH LLLAVGSILW
VCYVVYDELR GFIRIRQAYL TSPQHRIRAS ATTVLVSGIP RKWLTMEALS GLYDVFPGGI
RNIWINRDFD ELLEKVQLRD KTARQLEDAE TVLIKKCVKS HKQAEAKKAK EQGHGLSRKQ
KKQQQELENE QADQTAQGQG TSSGDPHKTR KNIHDAVDDF DHEEEEQRHR HEKKPELDLK
NPLKLMGQGL GAIGHGITAL GQKSKNLVEE VADDFNQGVK TVNTTIDQAN QGGGFVADDT
IFETPSNTSS GRSGLPNTAP VRPRGDEPGR NDAPGLRVVR NNEFNGSTTS RRPQDISITN
SSPSQGPNSS PLPSADERTS NGHPRSMDAL RPLEQKTPQQ HPPGMRGVAS KVKAYKNKTA
IPCPSPSPQA VEMDPLDNSG HAKAGETVRP QDRVAKSKWA EAWSKTQFWR KSGEEPVVVD
YPQAVVQECA EDQDGEPEWK KYIEVKDRET MRLPIASWMF SLPLIGQKVD RIYHLRKELA
RLNAEIETDQ NDHDRYPLLN SAFIQFHNQV AAHMACQSVS HHLPQHMTPR LVEISPSDVI
WSNMSIRWWE RYVRTGLVIA ACIGLIIFFA IPVGFTGLLS QVNVLGQRYS WLAWLSDLPP
TVISIIQGIL PPVLLAVLLA IVPMIFRFLV QQQGVATGND KELGVQNFYF IFLFFQVFLV
VTLSSGLTNF LTNLANNTTG VLLGLARDLP KSSNYFYSYL VVQALGSSAG VLLQVGTLLF
WFILGPILDS TARQKWARQT NLQTIQWGSY FPPFCNFAVI GLIFSVISPL IMLFNLVTFS
LFLAVQRYNV IYVYQFRVDT GGLLFPQAIN QLFTGLYVME VALAGLFFIA QDSAGNNGAI
PQGIIMIIML AFTVIFQVLI NSAFAPLLRY LPITLEDEAV VRDEEFARAQ AAKFRGLLEE
EPEDRESEDI EDRLEKQERM EEEADRAAEA AEREKIREKR TSRGESRSTS RHMRGGSNHR
HSSMETKPTG ISSWAHRARN PTDALKNFAH PRGRSTTLEK GGFTERTPAG KEVGNGNRYT
VAPNRRRQQE EQRQKDIESQ KLAGDVLFSG FSDELEDLTP EERDSLVRYS FQHAALRARR
PVIWIPRDVL GVSDDEIARS KLMSTVAAED SEGEKGAEAD GGETKTYIWM SNEGTALDAK
NRVVFRKSPP DFASVDLIAL
//
