ID A0A2K1R0E4_9PEZI Unreviewed; 997 AA.
AC A0A2K1R0E4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Calcium permeable stress-gated cation channel 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CAC42_2703 {ECO:0000313|EMBL:PNS20772.1};
OS Sphaceloma murrayae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Myriangiales; Elsinoaceae; Sphaceloma.
OX NCBI_TaxID=2082308 {ECO:0000313|EMBL:PNS20772.1, ECO:0000313|Proteomes:UP000243797};
RN [1] {ECO:0000313|EMBL:PNS20772.1, ECO:0000313|Proteomes:UP000243797}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CQ-2017a {ECO:0000313|EMBL:PNS20772.1,
RC ECO:0000313|Proteomes:UP000243797};
RA Cheng Q.;
RT "Draft genome sequence of a variant of Elsinoe murrayae.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNS20772.1}.
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DR EMBL; NKHZ01000017; PNS20772.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K1R0E4; -.
DR InParanoid; A0A2K1R0E4; -.
DR OrthoDB; 1330110at2759; -.
DR Proteomes; UP000243797; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF154; DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11660)-RELATED; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000243797};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 42..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..516
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 536..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 607..634
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 661..681
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 687..707
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 42..196
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 219..385
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 397..679
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 864..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 315..342
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 906..920
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 997 AA; 111582 MW; 0397AB055A2476C6 CRC64;
MEPSRVAHVA PRQESSGINT GDPQVDTLLR LLSGGFQTQS TAFLAAVASS LAITAAIITL
FCFLRPLNNV VYAPRAKYAD SKHVPPPVAK SPLAWVGIVF KTQEAELVDK LGLDATIFLR
FARMNRNIMI ALTIVGCGIL LPTNLIAGRG MTRAFSGIEF IPRLTPQFLY QSPAFWAYVV
VAYLFDIIIC YFLWRNYGAI ARLRRNYFDS AEYQQSLAAR TLLITEIPKD LRSNEGITSL
AEQTCPSADV PRAAIARNVK ELPELVSEHT ATVEQLEEVL AKYLKNPNKM PAQRPTCKVA
KKDAAYQKGK KVDAIEYLTN RIQNLERQIK EVRQSVDTRN AMNYGFASWQ NIADAHATAY
AARKGGAKKT VMRLAPKPHD FIWQNMPLTR KDRQWKNFVN NLWVAVLTVF WIAPNVFSAV
FLANLSNLGQ LWPAFQTSLS AYPTWWGIFQ GIAAPAIQSA FYYVLPIIFR RLSTRAGDQT
KTQRERHVLH KLFSFFVFNN LFIYSLFSAL WSYGVAVIGA TQRGDNWYDA LVEGKLFNLV
MLSLISMSTF WLTWLLQRNL GAAIDLAQLV NLGWGSFSRR FLSPTPRQLI KLSAPQPFDY
AGYYNYFLFY MTVALCYAPL QPLVLPVTAF YFWLDNFMKK YLLMYVFITK TESGGKFWRV
LFNRIIFNAL FGNAIIALVV VAQGDSWAML GALGPLPFLM LGFKWYCAKT FDPQIEYYTT
KVDNEQNVAS KEMRKGTEKV GVRFGHPVLY KPLITPMVHA KAQHMLSQIY TGRTSVEMDD
DNTVSGYSDV YMNPMAHNRP GKSAGPTNAP FEIVGENELN FEHWKNKAEF RDAAGGDGEL
FGRSADMIRR GSEQSTMTEM LYGAAQSRPD SRASGTRSRS DSVGSDRTKV EGVQYPAGYH
QPGRMGSNLR DQSVGSESGR SEWGTGEDGR GDLLGGAARM GRSPPPGRVP VGSRGPASRD
GSRGPLNRYE TGAWAPGETP GQTPGEDTSY DYFRGRR
//
