ID A0A2K1X1X3_POPTR Unreviewed; 1768 AA.
AC A0A2K1X1X3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Homeobox domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=POPTR_017G016200 {ECO:0000313|EMBL:PNS94769.1};
OS Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp.
OS trichocarpa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=3694 {ECO:0000313|EMBL:PNS94769.1, ECO:0000313|Proteomes:UP000006729};
RN [1] {ECO:0000313|EMBL:PNS94769.1, ECO:0000313|Proteomes:UP000006729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nisqually {ECO:0000313|Proteomes:UP000006729};
RX PubMed=16973872; DOI=10.1126/science.1128691;
RA Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I.,
RA Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J.,
RA Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W.,
RA Brun A., Brunner A., Busov V., Campbell M., Carlson J., Chalot M.,
RA Chapman J., Chen G.L., Cooper D., Coutinho P.M., Couturier J., Covert S.,
RA Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A.,
RA Depamphilis C., Detter J., Dirks B., Dubchak I., Duplessis S., Ehlting J.,
RA Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J., Groover A.,
RA Gunter L., Hamberger B., Heinze B., Helariutta Y., Henrissat B.,
RA Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S.,
RA Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjarvi J., Karlsson J.,
RA Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F.,
RA Leebens-Mack J., Leple J.C., Locascio P., Lou Y., Lucas S., Martin F.,
RA Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O.,
RA Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J.,
RA Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J.,
RA Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A.,
RA Tsai C.J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S.,
RA Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y.,
RA Rokhsar D.;
RT "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).";
RL Science 313:1596-1604(2006).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR EMBL; CM009306; PNS94769.1; -; Genomic_DNA.
DR SMR; A0A2K1X1X3; -.
DR STRING; 3694.A0A2K1X1X3; -.
DR InParanoid; A0A2K1X1X3; -.
DR OrthoDB; 394285at2759; -.
DR Proteomes; UP000006729; Chromosome 17.
DR ExpressionAtlas; A0A2K1X1X3; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR007759; Asxl_HARE-HTH.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR044977; RLT1-3.
DR InterPro; IPR028942; WHIM1_dom.
DR InterPro; IPR028941; WHIM2_dom.
DR PANTHER; PTHR36968; HOMEOBOX-DDT DOMAIN PROTEIN RLT2; 1.
DR PANTHER; PTHR36968:SF5; HOMEOBOX-DDT DOMAIN PROTEIN RLT2; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF05066; HARE-HTH; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF15612; WHIM1; 1.
DR Pfam; PF15613; WSD; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS51913; HTH_HARE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000006729};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT DOMAIN 25..85
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 560..619
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 742..811
FT /note="HTH HARE-type"
FT /evidence="ECO:0000259|PROSITE:PS51913"
FT DNA_BIND 27..86
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 838..880
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1566..1645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1676..1768
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 385..487
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 13..37
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 842..864
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 865..880
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1581..1598
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1615..1631
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1676..1690
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1724..1755
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1768 AA; 197881 MW; 0D6DC72CCD0BF581 CRC64;
MEEASSGGGS GGVEVEEKKK TPGEGESKSK RKMKTASQLE ILEKTYAADT YPSEAVRAEL
SVQLGLSDRQ LQMWFCHRRL KDRKAPLVKR PHKESPSPAG MPGGVEMGVG TEVGNEHGSG
SASLSGLGVD SRRAVGRPTG VAVPRISADV QAMKRYYEPQ QSVAELRAIA FVEAQLGEPL
REDGPILGIE FDPLPPDAFG APIRSATLGQ QKQPVRIFET NLYERPDIKP IKGTTRTLHE
YQFLPQQPTV KAEAYERAAP SFQYGSPADG HNTKTGSLSA TRSFMHANEQ VSSGYGFSSQ
VPSLTLMPQE GRQGHLLPSA TGEYENTSQK IPFTNVGMDV QIGAHPITAL DNPFMSSDQR
VTHDENALRM ERKRKSEEAR IAREVEAHEK RIRKELEKQD ILNRKREEQI RKEMERHDRE
RRKEEERLLR EKQREVERHQ REQRRELERR EKFLQKESIR VEKMRQKEEL RRQREAARQK
AASERAIARR MAKESLELVE DERLELMELA ASSKGLPSII PLDFETLQNL DLFRDKLTKF
PPKSVLLKRP FLIQPWNGSE ENIGNLLMVW RFLITFVDVL GIWPFTLDEF VQAFHDYEPR
LLGEIHISLL KSIIKDIEDV ARTPATSLGP NQNSAANPGG GHPQIVEGAY AWGFDIRSWQ
RHLNPLTWPE ILRQFGLSAG FGPQLKKRNV EQAYLCDDNE GNDGEDVITN LRNGAAVENA
FAIMQERGFS NPRRSRHRLT PGTVKFASFH VLSLEGSKGL TILEVADKIQ KSGLRDLTTS
KTPEASIAAA LSRDSKLFER TAPSTYCVRP PYRKDPADAE AILSAARERI RVFKSGIVDG
EDADDAERDE DSESDVAEDP DIDDLGTELN SKKEAHDSPE VNEFNGKTLL MNGKESGDVL
KTPQVSLVNV GAGLTSLHSE GTNEVRGVAS SIDRSVDVAE ICTTPVQGDV DIDESNPGEP
WVQGLADGEY SDLSVEERLS ALVALIGVAI EGNSIRIVLE ERLEAANALK KQMWAEAQLD
KRRMKEEFVM RTQYSSFTGN KMELNLTISA SEGRQSPMVN VDDRSNGMSV NASFQQERSS
DQQSDMNYLT NMSSEGNMQM QDLSADTDNL PYQQTGHANE KSRSQLKSVI GHRAEEMYVY
RSLPLGQDRR RNRYWQFTTS ASRNDPGCGR IFVELHDGRW RVIDSEEGFN ALLSSLDVRG
VRESHLHAML HKIEVPFKET LRKRMLHAST EGKSKGPIKA EAVETAAGIE CGSGMDSPQS
TVCIPDSDMS ETSTSFTIEL GRNEIEKNHA LKRFQDFEKW MWKECFKSSV LCAMKYGKKR
CTQRLGVCDY CHDTYLSEDN HCPSCHKTYD ASQVGLNISE HVAHCERKLK VDPDSALCSS
SFPLRIRLLK LLLALIEVSV LPEALQPVWT DDYRKSWGMK LQSSSSVEDL LQILTLLEGG
MKRDYLSSNY ETSSELLRSS DPSGCAAYGS FNTETVPVLP WLPQTTAAVA LRVIEFDASI
SYMLHQKPEA HKDRSTRSFI KLPSKYAAMK NTPDHEITES SRKAGLFQED NWVDVGIGLA
GLGREQGIRG RGRGRTRGGR SQTRIIGSRS VSSKRSAAKS SDRLGKALSW KGRPRGRGGC
KRGRRSVRSR QKAVKQASDF IPERKIPQET IREQSTNCLG RDDWNGDETR FVEDAENASS
SERSEYDDEN ENILASGDEY DNMRVDDYAG GFNGKSDDLL EGSDYVMDGN EDDDDAVNED
ELGDLDVEEY INGDPDDGTE SSSSDFID
//
