ID A0A2K1XNB0_POPTR Unreviewed; 759 AA.
AC A0A2K1XNB0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN ORFNames=POPTR_014G001500 {ECO:0000313|EMBL:PNT02265.1};
OS Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp.
OS trichocarpa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=3694 {ECO:0000313|EMBL:PNT02265.1, ECO:0000313|Proteomes:UP000006729};
RN [1] {ECO:0000313|EMBL:PNT02265.1, ECO:0000313|Proteomes:UP000006729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nisqually {ECO:0000313|Proteomes:UP000006729};
RX PubMed=16973872; DOI=10.1126/science.1128691;
RA Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I.,
RA Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J.,
RA Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W.,
RA Brun A., Brunner A., Busov V., Campbell M., Carlson J., Chalot M.,
RA Chapman J., Chen G.L., Cooper D., Coutinho P.M., Couturier J., Covert S.,
RA Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A.,
RA Depamphilis C., Detter J., Dirks B., Dubchak I., Duplessis S., Ehlting J.,
RA Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J., Groover A.,
RA Gunter L., Hamberger B., Heinze B., Helariutta Y., Henrissat B.,
RA Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S.,
RA Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjarvi J., Karlsson J.,
RA Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F.,
RA Leebens-Mack J., Leple J.C., Locascio P., Lou Y., Lucas S., Martin F.,
RA Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O.,
RA Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J.,
RA Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J.,
RA Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A.,
RA Tsai C.J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S.,
RA Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y.,
RA Rokhsar D.;
RT "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).";
RL Science 313:1596-1604(2006).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
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DR EMBL; CM009303; PNT02265.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K1XNB0; -.
DR STRING; 3694.A0A2K1XNB0; -.
DR InParanoid; A0A2K1XNB0; -.
DR OMA; VYVECTS; -.
DR OrthoDB; 493576at2759; -.
DR Proteomes; UP000006729; Chromosome 14.
DR ExpressionAtlas; A0A2K1XNB0; baseline.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0042300; F:beta-amyrin synthase activity; IBA:GO_Central.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IBA:GO_Central.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11764:SF90; TERPENE CYCLASE_MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|RuleBase:RU362003};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006729};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 605..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 99..399
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 412..750
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 759 AA; 87864 MW; 8FC22C96AFA13B64 CRC64;
MWRLKIAEKG SNPYIFSTND FVGRQIWAYD PNAGTPEERE QVEEARRNFT RNRSEVKPSS
DLLWQYQILR EKNFKQTIPA VRVEDGEEVT YEKTTTALRR SANFLSALQA SDGHWPAENS
GVLFFLPPFV FCFYITGHLN TMFPPEYRKE IFRYIYNHQN EDGGWGLHIE SHSNMFCTTF
SYICLRMLGV APDEEACARG RKWILDRGGV TSIPSWGKTW LSILGLFDWL GCNPMPPEFW
ILPSTLPIHP AKMWCYTRLV YMPMSYLYGK RFVGPITPLI LSLREELYLQ PYESVNWKHV
RHLCAKEDLY YPHTLIQDFL WDSLYLMSEP LLTRWPFNQL IRKKALEVTM KHIHYEDESS
RYITIGCIEK VLCMLSCWVE DPDGVAFKRH LARVPDFLWV GEDGMKVQTF GSQLWDATFG
FQALYSSDLG EEIKPTLAKA FDFIKKCQVV DNPAGDFRGM YRHISRGSWT FSDQDHGWQV
SDCTAEALKC VLFAQMLPSE YVGEKLDPRM IFEAVNIILS LQGPRGGLSG WETIRGEMWL
EKLNPLEFAE NIVIEHDYTE CTSSAIQVFV MFMKMYPGHR KKEIETSIAR AVEYLKMIQM
PDGSWYGNWG VCFIYSTWYA LVGLAAAGKT YYNNQAMRRG VDFLLRVQSP DGGWGESYLS
CPNKIYTSLE ENRSTYVQSA WAMLGLIHAG QADRDPTPLH RAAKLLINSQ AEDGSYPQQE
ITGVFKNNCM LHYPIHKNVF PLWALAEYRK KFPFPSKKL
//
