ID A0A2K1Y0I1_POPTR Unreviewed; 965 AA.
AC A0A2K1Y0I1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=5'-3' exoribonuclease {ECO:0000256|PIRNR:PIRNR037239};
DE EC=3.1.13.- {ECO:0000256|PIRNR:PIRNR037239};
GN ORFNames=POPTR_013G035600 {ECO:0000313|EMBL:PNT06530.1};
OS Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp.
OS trichocarpa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=3694 {ECO:0000313|EMBL:PNT06530.1, ECO:0000313|Proteomes:UP000006729};
RN [1] {ECO:0000313|EMBL:PNT06530.1, ECO:0000313|Proteomes:UP000006729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nisqually {ECO:0000313|Proteomes:UP000006729};
RX PubMed=16973872; DOI=10.1126/science.1128691;
RA Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I.,
RA Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J.,
RA Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W.,
RA Brun A., Brunner A., Busov V., Campbell M., Carlson J., Chalot M.,
RA Chapman J., Chen G.L., Cooper D., Coutinho P.M., Couturier J., Covert S.,
RA Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A.,
RA Depamphilis C., Detter J., Dirks B., Dubchak I., Duplessis S., Ehlting J.,
RA Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J., Groover A.,
RA Gunter L., Hamberger B., Heinze B., Helariutta Y., Henrissat B.,
RA Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S.,
RA Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjarvi J., Karlsson J.,
RA Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F.,
RA Leebens-Mack J., Leple J.C., Locascio P., Lou Y., Lucas S., Martin F.,
RA Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O.,
RA Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J.,
RA Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J.,
RA Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A.,
RA Tsai C.J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S.,
RA Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y.,
RA Rokhsar D.;
RT "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).";
RL Science 313:1596-1604(2006).
CC -!- FUNCTION: Possesses 5'->3' exoribonuclease activity. Acts as an
CC endogenous post-transcriptional gene silencing (PTGS) suppressor.
CC {ECO:0000256|PIRNR:PIRNR037239}.
CC -!- SIMILARITY: Belongs to the 5'-3' exonuclease family. XRN2/RAT1
CC subfamily. {ECO:0000256|ARBA:ARBA00006994,
CC ECO:0000256|PIRNR:PIRNR037239}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM009302; PNT06530.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K1Y0I1; -.
DR STRING; 3694.A0A2K1Y0I1; -.
DR InParanoid; A0A2K1Y0I1; -.
DR OMA; AFLYQMC; -.
DR OrthoDB; 167745at2759; -.
DR Proteomes; UP000006729; Chromosome 13.
DR ExpressionAtlas; A0A2K1Y0I1; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0004534; F:5'-3' RNA exonuclease activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-UniRule.
DR GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IBA:GO_Central.
DR CDD; cd18673; PIN_XRN1-2-like; 1.
DR Gene3D; 1.25.40.1050; -; 1.
DR Gene3D; 3.40.50.12390; -; 1.
DR InterPro; IPR027073; 5_3_exoribonuclease.
DR InterPro; IPR041412; Xrn1_helical.
DR InterPro; IPR004859; Xrn1_N.
DR InterPro; IPR017151; Xrn2/3/4.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR12341:SF74; 5'-3' EXORIBONUCLEASE 4; 1.
DR PANTHER; PTHR12341; 5'->3' EXORIBONUCLEASE; 1.
DR Pfam; PF17846; XRN_M; 2.
DR Pfam; PF03159; XRN_N; 1.
DR Pfam; PF00098; zf-CCHC; 1.
DR PIRSF; PIRSF037239; Exonuclease_Xrn2; 2.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000256|PIRNR:PIRNR037239};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR037239};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664,
KW ECO:0000256|PIRNR:PIRNR037239};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|PIRNR:PIRNR037239};
KW Reference proteome {ECO:0000313|Proteomes:UP000006729};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 264..279
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT REGION 23..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 878..908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 119..146
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 884..908
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 965 AA; 110599 MW; 74892D49F737F419 CRC64;
MGVPAFYRLL ADRYPLSISD VIEEEPQEDS NGNSKPIDVS KPNPNGIEFD NLYLDMNGII
HPCFHPEGKP APATYDDVFK SIFAYIDHLF ALVRPRKLLF MAIDGVAPRA KMNQQRSRRF
RAAKDAAQAE AEEERLRKEF EAEGELLSVK EKPETFDSNV ITPGTQFMAA LSTALQYYIQ
SRLNHNLGWQ NTKVILSDSN VPGEGEHKIM SYIRLQRNLS GFNPNTRHCL YSLDADLIML
SLATHEVHFS ILREIVTLPG QQDKCFLCGQ AGHLAAECRG KQGDDALDWH VVDDTPIHKK
KYQFLNIWVL REYLQYDLDI LNPPFAIDFE RIVDDFVFLC FFVGNDFLPH MPTLEIREGA
ISLLMHIYRR EFSAMGGYLT LAGEVFLDKV EHFIQCVGVY EEQIFQKRTR IQQAFDNNEE
MKLKARRESS EVIQAPVVDK VKLGEPGYKE RYYAEKFELS NQEEIDKVRK EVVLKYVEGL
CWVCHYYFQG VCSWQWFYPF HYAPFASDLK DLGEVELNFF IGEPFKPFDQ LMGTLPAASS
NALPKEYRKL MTNPSSPIHR FFPSDFEIDM NGKRFAWQGI AKLPFIDERK LLAQTKKLES
TLTEEEQIRN RVMLDLLYIH PVHPLAQLVI SYYQQNDHLS EGERFAWEID TRASGGMNGC
LWLYERNVRR SVVPSPILGL PVLEGNQVLN ITFLNPKNRA HIPEIPEGVV MPEKIVKPVD
LKPFPTLWHE DNGRRQQGRE RPQVQRAIAG PFLGDAAHRL VKNTLNIKPN GSSSRVFDQQ
LYHSIPGNYT FYRPRPAGPA GYGRGYWDDP NYHYAQHSNQ QGLMSNPRYR SLSNGVQSNR
HNFRTQDGVQ YHQQYHNLST GVSALTVEEN IRSRAPAVIS PRMPNPGNTP NLQNQAEQNT
GLLSSPPTNW INKTAAGNTG MYFKQKSTSI GPNEKQVKQV YQVKTQVAQE TPDIQAQETP
DLKQQ
//
