ID A0A2K1Y0K8_POPTR Unreviewed; 1092 AA.
AC A0A2K1Y0K8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=POPTR_013G037300 {ECO:0000313|EMBL:PNT06561.1};
OS Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp.
OS trichocarpa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=3694 {ECO:0000313|EMBL:PNT06561.1, ECO:0000313|Proteomes:UP000006729};
RN [1] {ECO:0000313|EMBL:PNT06561.1, ECO:0000313|Proteomes:UP000006729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nisqually {ECO:0000313|Proteomes:UP000006729};
RX PubMed=16973872; DOI=10.1126/science.1128691;
RA Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I.,
RA Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J.,
RA Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W.,
RA Brun A., Brunner A., Busov V., Campbell M., Carlson J., Chalot M.,
RA Chapman J., Chen G.L., Cooper D., Coutinho P.M., Couturier J., Covert S.,
RA Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A.,
RA Depamphilis C., Detter J., Dirks B., Dubchak I., Duplessis S., Ehlting J.,
RA Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J., Groover A.,
RA Gunter L., Hamberger B., Heinze B., Helariutta Y., Henrissat B.,
RA Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S.,
RA Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjarvi J., Karlsson J.,
RA Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F.,
RA Leebens-Mack J., Leple J.C., Locascio P., Lou Y., Lucas S., Martin F.,
RA Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O.,
RA Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J.,
RA Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J.,
RA Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A.,
RA Tsai C.J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S.,
RA Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y.,
RA Rokhsar D.;
RT "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).";
RL Science 313:1596-1604(2006).
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DR EMBL; CM009302; PNT06561.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K1Y0K8; -.
DR InParanoid; A0A2K1Y0K8; -.
DR OMA; IHIRNID; -.
DR OrthoDB; 995586at2759; -.
DR Proteomes; UP000006729; Chromosome 13.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017:SF479; DISEASE RESISTANCE PROTEIN CHL1; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00369; LRR_TYP; 2.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000006729};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 34..203
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 1092 AA; 122481 MW; 4A07DDC282AD1D57 CRC64;
MASMFFETGS SFSSSSFFET GSSSSSSSSS LPRKTHDVFL SFRGEDTRRN FTDHLYNALV
QAGVHTFRDN DHLPRGEEIS SQLLEAIRGS KISIVVFSKG YATSTWCLEE LANIMGCRKK
KHQVVLPVFY DIDPSDVRKQ KRSFAEAFQT HEHFFKEDME KVNRWRKALR EASTLSGWDL
NTMANRHESD FIRNIVKDVL GKLCPKRLLY CPEHLVGIDS HVDNIIALLR IVTDDSRIVG
IHGMGGIGKT TLAKVLFNLL DCEFEGSTFL STVSDRSKAP NGLVLLQKQL LCDTLKTKNI
VTINNVDRGM ILITERLRCK RVLVVLDDVD NEYQVKALVG ENRFGPGSVI MVTSRNEHLL
NRFTVHVKYE AKLLTQDESL QLFSRHAFGT THPPEDYAEL SNDVLKCACA LPLALEVLGA
SLFGKNKSEW RSAIEKLRKT PDHDVQAKLK ISYDALDDDI LKNIFLDIAC FFVGRNKEYV
STILHARYGF NQEINLTILV QRSLLEVNLQ NQLRMHDLVR DMGRAIVYQM CPQHPGKRSR
IWLHEEAWEV LNMNMGTKQV EGLVLDVQTS NAEPLRTESF KNMKYLKLLQ INGVRLKGCY
RHLPIGIIWL CWHGCSLRSF PPKFHLDSLV VLDMQYSNIK ELKPLNNLKI LNLSNSKFAK
TPNFLDVSRL ERLILEDCRN LAEVHQSAGH LKVLVHLSLK GCYSLNNLPE SICNLKSLET
LDISMCSRLE NLPEHLGVME SLTELLADET AIRQLPSSVG QLKRLRKLSL SGCNSKQDSP
FTSWLSLISS WLSPTSSTSK VLLPASLSSL SLLRGLDLSY RGLSEGEISI DLGSLSSLQE
LNLSGNKFFN LPSSIGLLPK LNYLLVKDCT NLLSVPELPP SLMELDAVNC SALERLTINS
KRIPSLYVSG CKNLIEIEGM EGMGKRWVIV SEDRSNLSNN LKQSLVQALC KGEEYDIVIA
DGEMPELFSN RGEGSSLSFH IPPGSDGNKI QGLVAWVVCA IDGNISAYLR GEAVIKNKSN
GVQLFKRSIM LFTMSTNSSN QCSWVNHISL AALDPNAMKA GEELELSVEV KHTSFEVQKC
GVHMIVKKPE VE
//
