ID A0A2K1Y1N3_POPTR Unreviewed; 830 AA.
AC A0A2K1Y1N3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 2.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=CCR4-Not complex component Not N-terminal domain-containing protein {ECO:0000259|Pfam:PF04065};
GN ORFNames=POPTR_013G059800 {ECO:0000313|EMBL:PNT06948.2};
OS Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp.
OS trichocarpa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=3694 {ECO:0000313|EMBL:PNT06948.2, ECO:0000313|Proteomes:UP000006729};
RN [1] {ECO:0000313|EMBL:PNT06948.2, ECO:0000313|Proteomes:UP000006729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nisqually {ECO:0000313|Proteomes:UP000006729};
RX PubMed=16973872; DOI=10.1126/science.1128691;
RA Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I.,
RA Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J.,
RA Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W.,
RA Brun A., Brunner A., Busov V., Campbell M., Carlson J., Chalot M.,
RA Chapman J., Chen G.L., Cooper D., Coutinho P.M., Couturier J., Covert S.,
RA Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A.,
RA Depamphilis C., Detter J., Dirks B., Dubchak I., Duplessis S., Ehlting J.,
RA Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J., Groover A.,
RA Gunter L., Hamberger B., Heinze B., Helariutta Y., Henrissat B.,
RA Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S.,
RA Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjarvi J., Karlsson J.,
RA Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F.,
RA Leebens-Mack J., Leple J.C., Locascio P., Lou Y., Lucas S., Martin F.,
RA Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O.,
RA Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J.,
RA Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J.,
RA Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A.,
RA Tsai C.J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S.,
RA Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y.,
RA Rokhsar D.;
RT "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).";
RL Science 313:1596-1604(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR005290}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR005290}.
CC -!- SIMILARITY: Belongs to the CNOT2/3/5 family.
CC {ECO:0000256|ARBA:ARBA00007682, ECO:0000256|PIRNR:PIRNR005290}.
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DR EMBL; CM009302; PNT06948.2; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K1Y1N3; -.
DR Proteomes; UP000006729; Chromosome 13.
DR ExpressionAtlas; A0A2K1Y1N3; baseline and differential.
DR GO; GO:0030015; C:CCR4-NOT core complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-UniRule.
DR GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.30.30.1020; CCR4-NOT complex subunit 2/3/5, C-terminal domain; 1.
DR InterPro; IPR038635; CCR4-NOT_su2/3/5_C_sf.
DR InterPro; IPR012270; CCR4-NOT_su3/5.
DR InterPro; IPR040168; Not2/3/5.
DR InterPro; IPR007207; Not_N.
DR PANTHER; PTHR23326; CCR4 NOT-RELATED; 1.
DR PANTHER; PTHR23326:SF1; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3; 1.
DR Pfam; PF04065; Not3; 1.
DR PIRSF; PIRSF005290; NOT_su_3_5; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR005290};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005290};
KW Reference proteome {ECO:0000313|Proteomes:UP000006729};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|PIRNR:PIRNR005290};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR005290};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR005290}.
FT DOMAIN 4..236
FT /note="CCR4-Not complex component Not N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04065"
FT REGION 110..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 285..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 604..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 667..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..619
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 830 AA; 89895 MW; 041EBFEF088F2BBD CRC64;
MGASRKLQGE IDRVLKKVQE GVDVFDSIWN KVYDTDNVNQ KEKFEADLKK EIKKLQRYRD
QIKTWIQSSE IKDKKVSASY EQALVDARKT IEKEMERFKI CEKETKTKAF SKEGLGQQPK
TDPKEKAKSE TRDWLNNVVG ELESQIDSFE AEIEGLTVKK GKTRPPRLTH LEASITRHKL
HIKKLELILR LLDNDELSPE QVNDVKDFLD DYVERNQEDF DDFSDVDDLY NSLPLDKVES
LEDLVTIGPP GLVKGAPVHS LKTSLVTSAP QMPATVASTH HEGAVVQDQA DDTTSQDSNS
DIVARTPPAK SSMVGSSAAA TPTGNHAPIS VNVQAQTLHD LSAASPTLPG STSVRGVLEN
AAPFNPSSPA TLGNSMKEEE IAGFPGRRSS PSLADAGLAR GIGRGGLSSQ PSSSIPLSPV
VIPSNGAHGS VPLASDIAKR NILGNDDRIG SAGMVQPLAS PLSNRMILPQ AGDGTSAVDT
SSAGEAATMG GRVFSPLVTG MQWRPGSSFQ NQNEPGQFRA RTEIAPDQRE KFLQRLQQVQ
QQGHSNILGM PPLTGGNHKQ YSAQQNPLLQ QFNSQSSSVS QASLGLGVQA SGFNTVTSAA
LQQPNSIHQQ SSQQVVMSSG AKDAELGHST VDEQQLKQNL PEDSTTKSAL TSGLGKSLVN
EDELTSPYAM DTSAGASGSL TEPLQVPRDI DLSPGQLLQS SQPSSGLGVI GRRSVSDLGA
IGDNLTGSAV NSGAMHNQLY NLQMLEAAYH KLPQPKDSER ARSYIPRHPA ATPPSYPQVQ
LPMASNPAFW ERLSMHSYGT DTLFFAFYYQ QVMWHAMLFH YYAVFVSVIQ
//
