ID A0A2K2BJI0_POPTR Unreviewed; 431 AA.
AC A0A2K2BJI0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 2.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=diaminohydroxyphosphoribosylaminopyrimidine deaminase {ECO:0000256|ARBA:ARBA00012766};
DE EC=3.5.4.26 {ECO:0000256|ARBA:ARBA00012766};
GN ORFNames=POPTR_002G158800 {ECO:0000313|EMBL:PNT49932.2};
OS Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp.
OS trichocarpa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=3694 {ECO:0000313|EMBL:PNT49932.2, ECO:0000313|Proteomes:UP000006729};
RN [1] {ECO:0000313|EMBL:PNT49932.2, ECO:0000313|Proteomes:UP000006729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nisqually {ECO:0000313|Proteomes:UP000006729};
RX PubMed=16973872; DOI=10.1126/science.1128691;
RA Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I.,
RA Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J.,
RA Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W.,
RA Brun A., Brunner A., Busov V., Campbell M., Carlson J., Chalot M.,
RA Chapman J., Chen G.L., Cooper D., Coutinho P.M., Couturier J., Covert S.,
RA Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A.,
RA Depamphilis C., Detter J., Dirks B., Dubchak I., Duplessis S., Ehlting J.,
RA Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J., Groover A.,
RA Gunter L., Hamberger B., Heinze B., Helariutta Y., Henrissat B.,
RA Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S.,
RA Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjarvi J., Karlsson J.,
RA Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F.,
RA Leebens-Mack J., Leple J.C., Locascio P., Lou Y., Lucas S., Martin F.,
RA Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O.,
RA Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J.,
RA Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J.,
RA Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A.,
RA Tsai C.J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S.,
RA Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y.,
RA Rokhsar D.;
RT "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).";
RL Science 313:1596-1604(2006).
CC -!- PATHWAY: Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-
CC ribitylamino)uracil from GTP: step 2/4.
CC {ECO:0000256|ARBA:ARBA00004882}.
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DR EMBL; CM009291; PNT49932.2; -; Genomic_DNA.
DR RefSeq; XP_002302581.2; XM_002302545.2.
DR AlphaFoldDB; A0A2K2BJI0; -.
DR STRING; 3694.A0A2K2BJI0; -.
DR EnsemblPlants; Potri.002G158800.1.v4.1; Potri.002G158800.1.v4.1; Potri.002G158800.v4.1.
DR GeneID; 7461764; -.
DR Gramene; Potri.002G158800.1.v4.1; Potri.002G158800.1.v4.1; Potri.002G158800.v4.1.
DR KEGG; pop:7461764; -.
DR InParanoid; A0A2K2BJI0; -.
DR OrthoDB; 5490680at2759; -.
DR UniPathway; UPA00275; UER00401.
DR Proteomes; UP000006729; Chromosome 2.
DR GO; GO:0008835; F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009231; P:riboflavin biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd01284; Riboflavin_deaminase-reductase; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR Gene3D; 3.40.430.10; Dihydrofolate Reductase, subunit A; 1.
DR InterPro; IPR016192; APOBEC/CMP_deaminase_Zn-bd.
DR InterPro; IPR002125; CMP_dCMP_dom.
DR InterPro; IPR016193; Cytidine_deaminase-like.
DR InterPro; IPR024072; DHFR-like_dom_sf.
DR InterPro; IPR004794; Eubact_RibD.
DR NCBIfam; TIGR00326; eubact_ribD; 1.
DR PANTHER; PTHR11079; CYTOSINE DEAMINASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11079:SF162; RIBOFLAVIN BIOSYNTHESIS PROTEIN PYRD, CHLOROPLASTIC; 1.
DR Pfam; PF00383; dCMP_cyt_deam_1; 1.
DR SUPFAM; SSF53927; Cytidine deaminase-like; 1.
DR SUPFAM; SSF53597; Dihydrofolate reductase-like; 1.
DR PROSITE; PS00903; CYT_DCMP_DEAMINASES_1; 1.
DR PROSITE; PS51747; CYT_DCMP_DEAMINASES_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006729};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 78..200
FT /note="CMP/dCMP-type deaminase"
FT /evidence="ECO:0000259|PROSITE:PS51747"
SQ SEQUENCE 431 AA; 46802 MW; 8A02C190B8F6D537 CRC64;
MPAHTLTLPY HPPTPLNFSR SSRTLPSLAS PQYPLNLTLR DHSRSGFFNP VNRMSSSGKH
GILVTVSCVA KEGGDDDKDD GFYMRRCVEL ARKAIGCTSP NPMVGCVIVK DGKIVGEGFH
PKAGQPHAEV FALRDAEDLA ENATAYVSLE PCNHYGRTPP CSEALVKAKV KKVVIGMIDP
NPIVASRGVQ RLRDAGINVV VGVEEELCKR LNEAFIHKML TGSPFVTLRY SLSVNGHLVN
QLGEGVTDTG GYYSQLLQEY DAVILSASLT GSSPFPASQE PGANQPLWIL MAGGPSSPIQ
IPLLTEEAAS KVTIFTDKEA SEEPETSKKG IETVVLDKIN LNAILEYCKS RGLCSVLMDL
RGSFVELEEL LKDGTEQNLL QKIVVEVLPF WDESSGLSSL TASKSIRRRL KVNNLQPKIS
GDQSIVLEGY L
//
