ID A0A2K2CPC4_BRADI Unreviewed; 881 AA.
AC A0A2K2CPC4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BRADI_4g21842v3 {ECO:0000313|EMBL:PNT63863.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:PNT63863.1};
RN [1] {ECO:0000313|EMBL:PNT63863.1, ECO:0000313|EnsemblPlants:PNT63863}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:PNT63863.1,
RC ECO:0000313|EnsemblPlants:PNT63863};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:PNT63863.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:PNT63863.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:PNT63863}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:PNT63863};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM000883; PNT63863.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K2CPC4; -.
DR EnsemblPlants; PNT63863; PNT63863; BRADI_4g21842v3.
DR Gramene; PNT63863; PNT63863; BRADI_4g21842v3.
DR InParanoid; A0A2K2CPC4; -.
DR Proteomes; UP000008810; Chromosome 4.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0098542; P:defense response to other organism; IBA:GO_Central.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1046; OS04G0219600 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT DOMAIN 5..101
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 171..391
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 881 AA; 100742 MW; 1E974047F17DE8F2 CRC64;
MSEVVLLAVS KITSVLAEEA TMAAIAKLSE KVTGLKELPS KVMNIKQELS VMNNVIRKIG
SHHDFKDEVV NSWISEVCNI AYHVQDVMDK CSYHVLQINE EGFLKQVFKK GTRNVKVFRE
IADEVFEVQN EIQQVRKMGQ QLLSRCFHVG TNIKFVKEDL VGIRDNRILL TGWLYSEEPE
GTVITVSRMG GLGKSTLATN VYKREKINFP AHAWIVVSQI YTVDALLRKL LWKIGYTEQP
LSAGIDKMDV HDLKKEIQPR LQNKIYLIVL DDVWEPEVYF QIHDVFHNLQ GSRIIITTRK
DHVAGISSST RHLELQPLIN RDAFDLFCRR AFYNKKGHVC PSELEDIADS IVDRCRGLPL
VIVTIGSMLS YRQQLDFWKQ TYNQLQSELS KNGHVRAIFH QSYHDLSDHR RNCFLYCCLF
PEDHFMSRDI LVRLWVAEGF VLSKDKNTPE MVAEGNLMEL ISCNMLEVVD YDELGRVNTC
KMHNIVRELA ISVAKKQGFA SANDYGTVIQ IDRDVRRLAS YGWKDDTALK VKLPRLRTVL
APGVISLYPN TLSSILSGSS YLNVLELQDS EVTEVPASIG HLFNLKYIGL RRTKVKSLPE
SIQKLSNLQT LDIKQTKIEK LPRGLGKITK LRHLLADRYD GEKWAESGYF IGVQSPKELS
NLAELQTLET VESSNDLAEQ LKKLMQLRSV CIDNISAADC ANLYASKDEN EALCFKDLKP
RSADLHKLVI RGQWAKGTLN CPIFLSHRIY LKYLALSWCH LGEDPLEILA QHLPYLRFLK
LNNMHSASTL VLTADSFPYL HTLVLEHMHD VSRLNFIDGA LPCIEVLHIV SLPKLDKVPQ
GIESLRSLKK LWLLDLHKNF RIQRDSNEMH QKMLHVPEVR V
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