ID A0A2K2CQ41_BRADI Unreviewed; 1167 AA.
AC A0A2K2CQ41;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Disease resistance protein RPM1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=BRADI_4g25041v3 {ECO:0000313|EMBL:PNT64146.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:PNT64146.1};
RN [1] {ECO:0000313|EMBL:PNT64146.1, ECO:0000313|EnsemblPlants:PNT64146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:PNT64146.1,
RC ECO:0000313|EnsemblPlants:PNT64146};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:PNT64146.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:PNT64146.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:PNT64146}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:PNT64146};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM000883; PNT64146.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K2CQ41; -.
DR STRING; 15368.A0A2K2CQ41; -.
DR EnsemblPlants; PNT64146; PNT64146; BRADI_4g25041v3.
DR Gramene; PNT64146; PNT64146; BRADI_4g25041v3.
DR InParanoid; A0A2K2CQ41; -.
DR Proteomes; UP000008810; Chromosome 4.
DR ExpressionAtlas; A0A2K2CQ41; baseline and differential.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0098542; P:defense response to other organism; IBA:GO_Central.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1114; OS02G0475500 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 2.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF52047; RNI-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT DOMAIN 16..99
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 189..376
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 448..690
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT REGION 391..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1167 AA; 130776 MW; BBF761B63BCB748E CRC64;
MEATVVSVGK AVLDGALGYA RSKAADELAL QLGMESDVAF IADELQMMQS FLATADEEDQ
PPQQQRVVAT WVTQVRDLAY DVEDSLMDCA LHSEKTKRNP APCSPWCWGQ GDRRHHISQE
VKTLRAKVED VSNRNLRYQL VKPQLQLPPA AAADQQLPSA MFGINEANLA TGAELELGGE
LAEDGDRLRR LLSSDEAELR VVAMWGTAGD PGKASAIKEA YDSSMAAAKF RLRAWVGLAR
PFDPTEFLRG LVRQFFFSHD NHESSSPGST TAGWADALMK MDMLDGGALA RMFDTQVGGN
SYLVVIDGLS TMVEWQCIKM YFPDKKNGSR IVVSTQHVEI ASLCTEKPYQ VSKLKRLSYH
QTLYLFHSKA RSGAAAAEPI VDSTRVTIAG NDPAMPAGEI QEEDQQSKDA EGDKVSNSSA
VSKVDRSRTM AQVEDMLTGR EMEKSKVIQL IGQPKESHSC KVISVWGMGG LGKTTLVRSV
YRSQQLGGWK RAWATALRPF NLEALLRNLA MQLQKGFHED PTGASATRTH KTNIASMKLH
ELEGELIRLL NTQKCLIELV KKCLESATRV IVTTREKIVA QQCSTEYSNI YSLQGLKDDA
ALDLFKRKSN GFGEYQFENL KRLVDMMEQA RLILKKCDGL PLAISAIAGY LATKPKTAIE
WAKMNGRISA ELEISPELRI IKTVLMRSYD GLPYHLKSCF LYMSLFPEDH IIKQNRLVRR
WIAEGYLRDM RGMTAEELGD KYLDELFSRS MILRVEWVNN YSAKLDACRL HDMIREICIL
KAREENLVFT LEEGCCLSGI QGALRHLVIS SNWKRDKDVL ESMLDLSHVR SMKVFGEWRS
FFISSKMRFL RVLDLEGTLG LQDHHLDQIG QLLHLKFFSL RGCRSIFFLP NSIGNLRHLE
TLDIRGTCIS QLPATVTKLQ KLQYLLPRGI GKLKALHTLG VVSIVRGKGE ATLKDLQELT
QLRKLGVAGI NNENINRFWS AIAGHSQLQS LSLHACTERD DLDGCLGGEL LPPKCLESLK
MYGKLVRVPR WIHQLPNLSR LELGHTHLHE EDIQALGMLP NLVALSLRRE SIQGDQLHFL
GSSFPRLVVL ELSVLTNVVS VRFGEGAMPK LELARAAWCK WIEEISGLTF LSSLREINLR
DVYSSTVTEE VQRQLMEHAN HVSLKLM
//
