ID A0A2K2DEW4_BRADI Unreviewed; 497 AA.
AC A0A2K2DEW4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Protein cereblon {ECO:0008006|Google:ProtNLM};
GN Name=100828195 {ECO:0000313|EnsemblPlants:PNT72836};
GN ORFNames=BRADI_2g49550v3 {ECO:0000313|EMBL:PNT72836.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:PNT72836.1};
RN [1] {ECO:0000313|EMBL:PNT72836.1, ECO:0000313|EnsemblPlants:PNT72836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:PNT72836.1,
RC ECO:0000313|EnsemblPlants:PNT72836};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:PNT72836.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:PNT72836.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:PNT72836}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:PNT72836};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 4-toluene sulfonate uptake permease (TSUP)
CC (TC 2.A.102) family. {ECO:0000256|ARBA:ARBA00009142}.
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DR EMBL; CM000881; PNT72836.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K2DEW4; -.
DR STRING; 15368.A0A2K2DEW4; -.
DR EnsemblPlants; PNT72836; PNT72836; BRADI_2g49550v3.
DR Gramene; PNT72836; PNT72836; BRADI_2g49550v3.
DR InParanoid; A0A2K2DEW4; -.
DR Proteomes; UP000008810; Chromosome 2.
DR ExpressionAtlas; A0A2K2DEW4; baseline.
DR GO; GO:0031464; C:Cul4A-RING E3 ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR CDD; cd15777; CRBN_C_like; 1.
DR Gene3D; 1.20.58.1480; -; 1.
DR Gene3D; 2.30.130.40; LON domain-like; 1.
DR Gene3D; 2.170.150.20; Peptide methionine sulfoxide reductase; 1.
DR InterPro; IPR034750; CULT.
DR InterPro; IPR003111; Lon_prtase_N.
DR InterPro; IPR046336; Lon_prtase_N_sf.
DR InterPro; IPR015947; PUA-like_sf.
DR PANTHER; PTHR14255:SF23; ATP-DEPENDENT PROTEASE LA (LON) DOMAIN-CONTAINING PROTEIN-LIKE; 1.
DR PANTHER; PTHR14255; CEREBLON; 1.
DR Pfam; PF02190; LON_substr_bdg; 1.
DR SMART; SM00464; LON; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS51788; CULT; 1.
DR PROSITE; PS51787; LON_N; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT DOMAIN 92..365
FT /note="Lon N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51787"
FT DOMAIN 366..473
FT /note="CULT"
FT /evidence="ECO:0000259|PROSITE:PS51788"
FT REGION 27..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 55957 MW; 095087040DFD6ECC CRC64;
MAEQPAWMRR QMEQILELDM EELEVEEVDD SASSSSSDVS TFLRNTHGGG ETGTSEEVTI
NTSRASLHTY VGEVVDTRSR FAFLNGGEVL NLPMLYLQGF VLFPEATLTL RVIQPRFLAT
VDKAINHVDA PCMIGVVHVY RHINDGLHSV ASIGTTAEIH QVRQSGDGTS NVSTRGQQRF
RLRRSWIDAD EVPWGEVQII EEDTPSRTPR NAFVQLAANT GMCYFSNEDE DLMRELSWQN
HDCINEFDAS VNKTNMGDDD DLRFAERQRQ YRAACNSKMA LEAPLSFWPR WAYKMYDSYS
LARRAADLWR QIVANPSMDD HVRKPDLLSF CIGSKLPISG SARQELLEID GISYRLQREI
QLLKAFNLMR CRNCLVLIAR RSDMVVISNG CPVGAYVKPF DGAQEMITVY NASGLALYGN
PSEVHSWFPG YTWTIALCAA CESNIGWLFS AAKKNLVPKS FWGQPTRCWP DINPAKKGNY
SARAHNGSKQ GSRSLIR
//
