ID A0A2K2DUK4_BRADI Unreviewed; 1282 AA.
AC A0A2K2DUK4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=XPG-I domain-containing protein {ECO:0000259|SMART:SM00484};
GN Name=100824635 {ECO:0000313|EnsemblPlants:PNT77955};
GN ORFNames=BRADI_1g70850v3 {ECO:0000313|EMBL:PNT77955.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:PNT77955.1};
RN [1] {ECO:0000313|EMBL:PNT77955.1, ECO:0000313|EnsemblPlants:PNT77955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:PNT77955.1,
RC ECO:0000313|EnsemblPlants:PNT77955};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:PNT77955.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:PNT77955.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:PNT77955}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:PNT77955};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CM000880; PNT77955.1; -; Genomic_DNA.
DR RefSeq; XP_014753116.1; XM_014897630.1.
DR EnsemblPlants; PNT77955; PNT77955; BRADI_1g70850v3.
DR Gramene; PNT77955; PNT77955; BRADI_1g70850v3.
DR Proteomes; UP000008810; Chromosome 1.
DR ExpressionAtlas; A0A2K2DUK4; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR GO; GO:0006259; P:DNA metabolic process; IEA:UniProt.
DR CDD; cd09904; H3TH_XPG; 1.
DR CDD; cd09868; PIN_XPG_RAD2; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006086; XPG-I_dom.
DR InterPro; IPR006084; XPG/Rad2.
DR InterPro; IPR019974; XPG_CS.
DR PANTHER; PTHR16171:SF7; DNA EXCISION REPAIR PROTEIN ERCC-5; 1.
DR PANTHER; PTHR16171; DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED; 1.
DR Pfam; PF00867; XPG_I; 1.
DR PRINTS; PR00853; XPGRADSUPER.
DR SMART; SM00279; HhH2; 1.
DR SMART; SM00484; XPGI; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
DR PROSITE; PS00842; XPG_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT DOMAIN 699..768
FT /note="XPG-I"
FT /evidence="ECO:0000259|SMART:SM00484"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 158..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 242..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 505..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 823..868
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 990..1166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1206..1282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 641..675
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 170..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 246..262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..559
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..586
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 587..606
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 823..844
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 990..1017
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1077..1092
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1105..1130
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1147..1162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1240..1270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1282 AA; 141206 MW; 371EB6D69BBB3ABC CRC64;
MLAASLAAED EADLTDKGGH NSASVPLQQG TGIDEDENDD DEEMIFPVTT GDIDPAVLAS
LPPSMQLDLL VQMRERVMAE NRQKYQKIKK EPAKFSELQI QSYLKTVAFR REIEEVQRGA
AGKDVGGIQT SKIASEANRE FIFSSSFTGD KQTLAQRGVG EHNVDNVKSK REISSTVFKS
SPSSSSRSIN PHNSEPLRDF GPDVETYCDE RGRIRVSRVR AMGIRMTRDI QRNLDFIKEH
EQAKSTGQTD VGNGSTSNEE PPNFPEHLFE NDGLQSSVSF SEDFADITGD NHHTSSLIGG
SDGISEGSCH GSKGTIEISF VDDQIGVSDN DDKLFLHLVS GTSSNIFAAA DRFAKNTEES
DDNSEGIWEE GVIEETLSMK VDEKDRQSTP PDNCYNDDEV EWEDGGCDVP GVPSSSEYNQ
CKLTKGDIEE EALIQEAIKR SLEDSGKQET ENGIPEDLQM SVEDKSLQSY VVPKPTEASG
ISCSLSKAVA AEEIIKEIGI VNNSGEGGAV HDPDGQENEN QAQLESNDEQ AGTNRSYSLG
SISTSTVAAR PSHSSKVQDN DAIADAIRTP EWPKGEGHEV IEKNTSNSHK SKSNTNDHSI
GDTSKSPQKE LLMDKLVADT AMEKENDVQE DVNITTSEIN YAKLSENYDS HVISASNLEE
EISFLRQEQV NLGNERRKLE SHAESVSSEM FAECQELLQM FGLPYIIAPM EAEAQCAYME
INNLVDGVVT DDSDVFLFGA RNVYKNIFDD RKYVETYFMK DIESELGLTR DQLIRMALLL
GSDYTEGISG IGIVNAIEVV HAFSEEDGLQ KFREWIESPD PAILGKLEKE TSDGSTRRKS
GGNESSEKGN SLEPECVEGS DGKHSSNETE HIKKIFMNKH RNVSKNWHIP STFPSETVIS
AYISPQVDDS TERFSWGRPD LSLLRKLCWE RFGWNKEKAD ELLLPVLREY NKHETQLRME
AFYSFNERFA KIRSKRIKKA IKGITGKTFS ETDELDHDSP STSEAPKKKE AGPSSHAKPR
GKRNSNAGPN SFAAADELAK EHSNASKKKT ASPSGRSRGR GRKRTNAGHE TAVSQEDSEV
KTSTFSSDVD THKSHAGNYK SEGTALRRSN RKRKQVTYME DGHEADDNDT PVYQADENDP
SPAASDIAGR DTQSNMFHQD TSELNRDQIH ADPGTAVDMS EDFEFCEDQT DSAPKEYLFT
GGGFCMEEDE EQDAPGDRPG AEIKDGTSDA FEDIGGVSDS GIDLSTTGEC AENASTESRG
ASSSKRGNVG LGLPTLTKRR RK
//
