ID   A0A2K2TN36_9CLOT        Unreviewed;       436 AA.
AC   A0A2K2TN36;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   RecName: Full=Histidine kinase/HSP90-like ATPase domain-containing protein {ECO:0000259|SMART:SM00387};
GN   ORFNames=C0033_23935 {ECO:0000313|EMBL:PNV59501.1};
OS   Clostridium sp. chh4-2.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=2067550 {ECO:0000313|EMBL:PNV59501.1, ECO:0000313|Proteomes:UP000236356};
RN   [1] {ECO:0000313|Proteomes:UP000236356}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=chh4-2 {ECO:0000313|Proteomes:UP000236356};
RA   Huang C.-H.;
RT   "Clostridium sp. nov. strain chh-4-2., isolated from the gut of a healthy
RT   Taiwan adult.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PNV59501.1}.
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DR   EMBL; PKUU01000030; PNV59501.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2K2TN36; -.
DR   OrthoDB; 9156435at2; -.
DR   Proteomes; UP000236356; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd16935; HATPase_AgrC-ComD-like; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR032834; NatK_C.
DR   PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   Pfam; PF14501; HATPase_c_5; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000236356};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        36..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        125..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        158..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          323..430
FT                   /note="Histidine kinase/HSP90-like ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00387"
SQ   SEQUENCE   436 AA;  49951 MW;  862F7CD63D170268 CRC64;
     MSQLFLAGEM AADFIEALLC YYFINLFVPQ KIKGRIRFVI LSVILLITMQ AADHFQIFPL
     ISTLWFVFYI CMTSVLVFQV DTFYSISLVS FYILCAYIID FFCLSVMGVL GKNQQFAQMV
     ISQLSLWRCA YLAVNKILLI LFYLLAKKAL KKELFYNASM IFTVSFLGLC GVGFLSWLTI
     QETSVHALFS WSMCIVLLFV FYFTLLFYTN YRKEKEISSI LQLKDQMVRR EYELVLGQQR
     QQQEMSHDLK NHMLVLSTLM EEERYEEVKS YISRLGEPLS RLSGEIWTGN ATLDILLSHF
     KNQGEQMEIP FTIQADAVDL SGMEDQDLCC LFANLLDNAL EAAQKMPQQK RWIQIKLRKI
     NEMIFIVISN SMSGRPVKQG DTLGSSKKET GMHGLGIRSA ARSAKKYGGA LEYEYGDGVF
     TVTVTFLEGL QPPCNP
//