ID A0A2K2TYS0_9CLOT Unreviewed; 212 AA.
AC A0A2K2TYS0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Cobalamin-binding protein {ECO:0000313|EMBL:PNV63217.1};
GN ORFNames=C0033_03775 {ECO:0000313|EMBL:PNV63217.1};
OS Clostridium sp. chh4-2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=2067550 {ECO:0000313|EMBL:PNV63217.1, ECO:0000313|Proteomes:UP000236356};
RN [1] {ECO:0000313|Proteomes:UP000236356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=chh4-2 {ECO:0000313|Proteomes:UP000236356};
RA Huang C.-H.;
RT "Clostridium sp. nov. strain chh-4-2., isolated from the gut of a healthy
RT Taiwan adult.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNV63217.1}.
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DR EMBL; PKUU01000003; PNV63217.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K2TYS0; -.
DR OrthoDB; 9803687at2; -.
DR Proteomes; UP000236356; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProt.
DR CDD; cd02070; corrinoid_protein_B12-BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR036594; Meth_synthase_dom.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR SMART; SM01018; B12-binding_2; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF47644; Methionine synthase domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51337; B12_BINDING_NTER; 1.
PE 4: Predicted;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000236356}.
FT DOMAIN 1..88
FT /note="B12-binding N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51337"
FT DOMAIN 88..212
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 212 AA; 22740 MW; 5D7EE3EAE1659B44 CRC64;
MAIIEEISEF LQKGRAKNVK VLVQQALDEG VDPKAILNDG LLSGMMIIGE KFKNNEVFVP
EVLVAARAMN AGIAILEPKL IEVGNEPVGR AVIGTVKGDL HDIGKNLVVM MLRGAGFEIY
DVGVDIESST FIDKAEEVGA DIICMSALLT TTMPNMKDVI DELNSRGLRD KYIVMVGGAP
VNESFAKQIG ADFYTPDAAT CADVAKQAVL SR
//
