ID A0A2K3CWI9_CHLRE Unreviewed; 755 AA.
AC A0A2K3CWI9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DUS-like FMN-binding domain-containing protein {ECO:0000259|Pfam:PF01207};
GN ORFNames=CHLRE_15g636896v5 {ECO:0000313|EMBL:PNW72646.1};
OS Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX NCBI_TaxID=3055 {ECO:0000313|EMBL:PNW72646.1, ECO:0000313|Proteomes:UP000006906};
RN [1] {ECO:0000313|EMBL:PNW72646.1, ECO:0000313|Proteomes:UP000006906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-503 {ECO:0000313|Proteomes:UP000006906};
RX PubMed=17932292; DOI=10.1126/science.1143609;
RA Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.,
RA Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT "The Chlamydomonas genome reveals the evolution of key animal and plant
RT functions.";
RL Science 318:245-250(2007).
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
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DR EMBL; CM008976; PNW72646.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K3CWI9; -.
DR STRING; 3055.A0A2K3CWI9; -.
DR EnsemblPlants; PNW72646; PNW72646; CHLRE_15g636896v5.
DR Gramene; PNW72646; PNW72646; CHLRE_15g636896v5.
DR InParanoid; A0A2K3CWI9; -.
DR OrthoDB; 103046at2759; -.
DR Proteomes; UP000006906; Chromosome 15.
DR ExpressionAtlas; A0A2K3CWI9; baseline and differential.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0017150; F:tRNA dihydrouridine synthase activity; IEA:InterPro.
DR CDD; cd02801; DUS_like_FMN; 1.
DR Gene3D; 1.20.120.1460; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR035587; DUS-like_FMN-bd.
DR InterPro; IPR004653; DusA.
DR InterPro; IPR018517; tRNA_hU_synthase_CS.
DR PANTHER; PTHR42907; FMN-LINKED OXIDOREDUCTASES SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR42907:SF1; FMN-LINKED OXIDOREDUCTASES SUPERFAMILY PROTEIN; 1.
DR Pfam; PF01207; Dus; 3.
DR SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
DR PROSITE; PS01136; UPF0034; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006906};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 16..136
FT /note="DUS-like FMN-binding"
FT /evidence="ECO:0000259|Pfam:PF01207"
FT DOMAIN 198..305
FT /note="DUS-like FMN-binding"
FT /evidence="ECO:0000259|Pfam:PF01207"
FT DOMAIN 441..538
FT /note="DUS-like FMN-binding"
FT /evidence="ECO:0000259|Pfam:PF01207"
FT REGION 343..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 395..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 562..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 734..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 125..159
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 343..357
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 395..420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 755 AA; 75127 MW; CAE42A1D60E56588 CRC64;
MQLPPNPAAA RPLLSVAPMM DWTDVHFRQL ARLVSRRVWL WTEMVVDKTV IHTPNLDKHL
WFPPEQRPLV LQLGGSDPAL LAAAAAKAAA YGYDEINLNC GCPSDRVAGA GCFGAALMMQ
PGLVADCMTA MAEALAAEAA AAEAEAAAAT AGAEAAEAAE AAATATAATV TAGGAEAEAA
GAAAETATAG AAAGAEAAGA AGAAAANGSR VGVTPVNVKC RLGVDECDSY AQLHEFVKVV
SERSPVTHFI VHSRKAFLNG LSPHQNRTVP PLRHQWAWAL ARDFPHLQFS LNGGLQTCHD
ARAALLTAHP EVPYTRPRLP HPGDPRAVAA AVCATATPTF TPLAIPPSLP PSSSSPAPAP
SSTSAASATP ESAAPAPAPV ASASSSLAAS SSSSASATVS PEAQPAASTS NGSSQSPAGN
GGGGLEGGHG SSQFPAGNGG GLEGVMIGRG AYNDPWGCLA DADRCLWGDD SNAAPNRRWV
IARYREYAEP MMGHWAVKAD GHCDPSVRTL MRPILNLFHG EKGSKRWKAA VDEVLKANPA
TFGEVLDKTL HLIPDEVLDA PPRTPDLADL PPFEMDPVLP LPHNRAGQNQ NPPGTPKEPK
EGGKEGGKEG GKKGANGGGG GPGKKKLAAK AAAAAVIAQE KAAAAAAAAA AAATAEGVGG
GVGCCAEAAA EAAEAAAAAE AAAAEAEAAG SGSESEGEGE GKAVAVAAAA APVAVTASAA
VAAAEGEAEA AAGQEAAVAA AGQAEKSRKG GCVVS
//
