ID A0A2K3D6S9_CHLRE Unreviewed; 1178 AA.
AC A0A2K3D6S9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=CHLRE_12g542450v5 {ECO:0000313|EMBL:PNW76241.1};
OS Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX NCBI_TaxID=3055 {ECO:0000313|EMBL:PNW76241.1, ECO:0000313|Proteomes:UP000006906};
RN [1] {ECO:0000313|EMBL:PNW76241.1, ECO:0000313|Proteomes:UP000006906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-503 {ECO:0000313|Proteomes:UP000006906};
RX PubMed=17932292; DOI=10.1126/science.1143609;
RA Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.,
RA Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT "The Chlamydomonas genome reveals the evolution of key animal and plant
RT functions.";
RL Science 318:245-250(2007).
CC -!- SIMILARITY: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005601}.
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DR EMBL; CM008973; PNW76241.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K3D6S9; -.
DR STRING; 3055.A0A2K3D6S9; -.
DR EnsemblPlants; PNW76241; PNW76241; CHLRE_12g542450v5.
DR Gramene; PNW76241; PNW76241; CHLRE_12g542450v5.
DR InParanoid; A0A2K3D6S9; -.
DR OrthoDB; 316745at2759; -.
DR Proteomes; UP000006906; Chromosome 12.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0043186; C:P granule; IBA:GO_Central.
DR GO; GO:0032574; F:5'-3' RNA helicase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0035194; P:regulatory ncRNA-mediated post-transcriptional gene silencing; IBA:GO_Central.
DR CDD; cd18038; DEXXQc_Helz-like; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR049080; MOV-10-like_beta-barrel.
DR InterPro; IPR026122; MOV-10/SDE3_DEXXQ/H-box.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF322; RNA HELICASE MOV10L1; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF21634; MOV-10_beta-barrel; 1.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000006906}.
FT DOMAIN 101..125
FT /note="C2H2-type"
FT /evidence="ECO:0000259|SMART:SM00355"
FT DOMAIN 153..177
FT /note="C2H2-type"
FT /evidence="ECO:0000259|SMART:SM00355"
FT REGION 319..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1178 AA; 126180 MW; 9E9C7035F610C6B5 CRC64;
MADAEEEVRA IAKELARKRA TKGSQTVSVG AIRVRAKKAG CRALMHKSNE DVKAWLAARP
EDYVLLGGDE VLVVAAVREG TEPSVPPGTR KRINKAAKRC LRCETCNIHT DNVPAMHAHI
LSQRHHNTVS RLTLDDVQRV LTAYRTRNTA DLQFCELCSE WLPGPNELKL HLRSRYHAVR
QCALLLRGGD LLGANAGGVV VSVLPDPLPA LEPGQTADYA FRISNLSGVK QSLLRVRLLQ
PVDGVQLSDA YGVSSGDGDG AGVGLPHGSS YEVAVRLAPR FRGVMRGVAV FEFGSGAQAV
RAIHAVCADA DTQAEMDAKT AAGGGSAQRR GRRLRRLEPQ NPDIVPGEAP AGADDHGARS
GCGRPPRLER PIGHHPVPRD VRGMVERCQW AELERRLCEA AGGEEAVAAA AAAAAAAAAG
GGCVEAAARA AALAARMPNV RAYAERLKLL TWLEELQHEV DVRTYDMREA RLEEIPRRSL
LALKVPGLAE NRPSVLKGDS IYVRPSDGTS GGREWEGIVH VVEREEVLLG FAASFRHGTW
VKGRAFDVRF AVNRSLFNKL QAVLSRTAAG DLNPLLLLPG GAAAPRLPPP PRDLPIDGPD
VDWLHPPPLE EERRRGSVAG AGGLMPAAPV RAKWGNRPLN AEQRLAVREV VRGAHAPLPY
IIYGPPGTGK TSTLVEAAVQ LLHAAPSAVL LAVAPSNSAA DQLMQRLLGA GRPKSEMMRV
CAYTRPDKDL PPDLDALRGT PQINWSDGAG AFLLPSKEQL TRPGLRVVVC TCATATMLYH
VGLPSGHFTH LLLDEAGHAE EPLLLAGLAG LAGPGCRVVM AGDPQQLGPV ILSPLAKRHG
LDTSLLERLT ATAPYSRRDA AKIGSASPRL PPYASAYLTK LLHNYRSHPD LLELPSAAFY
HGELVAAADP GVTHSLLHWE HLPNKRVPLL FHHLVGRDEQ EQSSPSWYNL DEAKQVVAYV
KSLKDMRRSR LNGDDIGVIS PYRKQVQRIR ALLRAVDDHI KVGSVEEFQG QERRVIIIST
VRSSREHMAL DARHRLGFLC NPKRFNVALT RAKALLVVVG CADVLATDPH WAAFLRLARD
HGAVTGQALP ELPPAPVSAA AAAAAAGAAA KAGEDEDGGG VVGQLAASLQ QLLLSAAVHG
DGAGGAVGGR GLLSDLEEQL RWLGGGLEME GGEMRRME
//
