ID A0A2K3D798_CHLRE Unreviewed; 969 AA.
AC A0A2K3D798;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Dynein axonemal assembly factor 4 {ECO:0000256|ARBA:ARBA00024430};
GN ORFNames=CHLRE_11g467560v5 {ECO:0000313|EMBL:PNW76404.1};
OS Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX NCBI_TaxID=3055 {ECO:0000313|EMBL:PNW76404.1, ECO:0000313|Proteomes:UP000006906};
RN [1] {ECO:0000313|EMBL:PNW76404.1, ECO:0000313|Proteomes:UP000006906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-503 {ECO:0000313|Proteomes:UP000006906};
RX PubMed=17932292; DOI=10.1126/science.1143609;
RA Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.,
RA Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT "The Chlamydomonas genome reveals the evolution of key animal and plant
RT functions.";
RL Science 318:245-250(2007).
CC -!- SUBCELLULAR LOCATION: Cell projection, neuron projection
CC {ECO:0000256|ARBA:ARBA00004487}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}. Dynein axonemal particle
CC {ECO:0000256|ARBA:ARBA00024190}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CM008972; PNW76404.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K3D798; -.
DR STRING; 3055.A0A2K3D798; -.
DR EnsemblPlants; PNW76404; PNW76404; CHLRE_11g467560v5.
DR Gramene; PNW76404; PNW76404; CHLRE_11g467560v5.
DR InParanoid; A0A2K3D798; -.
DR OrthoDB; 167568at2759; -.
DR Proteomes; UP000006906; Chromosome 11.
DR ExpressionAtlas; A0A2K3D798; baseline and differential.
DR GO; GO:0120293; C:dynein axonemal particle; IEA:UniProtKB-SubCell.
DR GO; GO:0043005; C:neuron projection; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003341; P:cilium movement; IBA:GO_Central.
DR GO; GO:0036159; P:inner dynein arm assembly; IBA:GO_Central.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR GO; GO:0036158; P:outer dynein arm assembly; IBA:GO_Central.
DR CDD; cd06469; p23_DYX1C1_like; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR037894; CS_DYX1C1.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR46492; DYNEIN ASSEMBLY FACTOR 4, AXONEMAL; 1.
DR PANTHER; PTHR46492:SF1; DYNEIN AXONEMAL ASSEMBLY FACTOR 4; 1.
DR Pfam; PF04969; CS; 1.
DR SMART; SM00028; TPR; 7.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS51203; CS; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000006906};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803}.
FT DOMAIN 2..86
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT REGION 116..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 163..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 890..969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..185
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..275
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 463..478
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 969 AA; 98477 MW; 3228A789C046C178 CRC64;
MPLAPKYTWT ETDVAIEVTV EVPGVSKSKA DVFATDAFLK VNSPPYLFAL DLAKDVDDTR
SSATILPGKV VFTLFKREPG VWGVLAATGE KAALTSRRNA SIDRAYAALE AARRARLERK
QHEDKAATQR TLDTDRRKRA EVEARKAAEL AAERGSLQQW QQRLGLGQEQ DAESDYEEED
EQADGAEEGR QQQQQAGGGE GRAAPDHPDY HGRGWRTSGA AAATGAAAAA GKAAGAAAAG
SAGLKAPGRG VDSEEEEDEG AERRAGGRGA GSDSEEEAEA AAPGPAAAGV GAGGAAAAGA
VAARPASFKP LPPPRARLEP VQVTFTQLET GHLPAREHRE EEIRAFRKQS RASALEAGAA
AGGGGDDAAD LSERQPLFLK DKGDAMFRAG NFSGALNAYH RAIALDDAAS AAASDPAAAA
PALRSNRAAC LLALGRAAEA AEDCDRALEL LVTFTQLETG HLPAREHREE EIRAFRKQPE
APRPGLNPGA ALAAPDSPKT TQSRASALEA GAAAGGGGDD AADLSERQPL FLKDKGDAMF
RAGNFSGALN AYHRAIALDD AASAAASDPA AAAPALRSNR AACLLALGRA AEAAEDCDRA
LELLAGARSR LESGLMGGPE AAALSQQLVR LLVRRAQARA AQLGAGGGGG GGGRDKDRDA
DNLCAALRDY EDAIKLAPSA AALAADRDEL LAALAPADAA ALRQRGDARF RAGDYEGAAE
AFSALLGLPR GGVPESERLA AFSNRAACHL VLERFAAAVA DCDAGLALLL LLQPQQQAQA
AASSSAFGMA AGGEGRRRLA EWAAASLPAA AAADASSPSG GAESAAAAQA AVSAARLLTR
RGAAAAHLQD FAAAAEDHAL AAALLRRLPG PEHAAKAEAA EADAARMRAL AEGREQPPSR
PAAEAASASQ PVVKAEAAEG VEAGGLEGAG EGRGAGGEQQ QTCEVAGGGA VAAGGRGAGE
GLADDDVDD
//
