ID A0A2K3DD15_CHLRE Unreviewed; 1051 AA.
AC A0A2K3DD15;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=U-box domain-containing protein {ECO:0000259|PROSITE:PS51698};
GN ORFNames=CHLRE_09g398350v5 {ECO:0000313|EMBL:PNW78417.1};
OS Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX NCBI_TaxID=3055 {ECO:0000313|EMBL:PNW78417.1, ECO:0000313|Proteomes:UP000006906};
RN [1] {ECO:0000313|EMBL:PNW78417.1, ECO:0000313|Proteomes:UP000006906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-503 {ECO:0000313|Proteomes:UP000006906};
RX PubMed=17932292; DOI=10.1126/science.1143609;
RA Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.,
RA Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT "The Chlamydomonas genome reveals the evolution of key animal and plant
RT functions.";
RL Science 318:245-250(2007).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ubiquitin conjugation factor E4 family.
CC {ECO:0000256|ARBA:ARBA00007434}.
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DR EMBL; CM008970; PNW78417.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K3DD15; -.
DR STRING; 3055.A0A2K3DD15; -.
DR PaxDb; 3055-EDP02513; -.
DR EnsemblPlants; PNW78417; PNW78417; CHLRE_09g398350v5.
DR Gramene; PNW78417; PNW78417; CHLRE_09g398350v5.
DR InParanoid; A0A2K3DD15; -.
DR OMA; WLTEIAM; -.
DR OrthoDB; 1554at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000006906; Chromosome 9.
DR ExpressionAtlas; A0A2K3DD15; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0034450; F:ubiquitin-ubiquitin ligase activity; IBA:GO_Central.
DR GO; GO:0000209; P:protein polyubiquitination; IBA:GO_Central.
DR GO; GO:0030433; P:ubiquitin-dependent ERAD pathway; IBA:GO_Central.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR019474; Ub_conjug_fac_E4_core.
DR InterPro; IPR045132; UBE4.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13931:SF2; UBIQUITIN CONJUGATION FACTOR E4 B; 1.
DR PANTHER; PTHR13931; UBIQUITINATION FACTOR E4; 1.
DR Pfam; PF04564; U-box; 1.
DR Pfam; PF10408; Ufd2P_core; 1.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000006906}.
FT DOMAIN 976..1049
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REGION 432..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1011..1030
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..452
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1051 AA; 114954 MW; 1A4664ED1714BC2B CRC64;
MGDAEQVFSR IFTLKLYGQP ELGGKTPALV LSQLAAELEA EAEEGAAKPV LDATVLDRML
VARLIEAPPA DYPQPPIHYL MGCYERSSEE LRRAGVSEAA KAAVATARDL ILNYAGLALF
AGMIPQPPVL EARGPLQLLD ALLLRHGLSV VALTTVVTPA FASAGGQAAA SAYAAAATPM
PPGFLEELAV RHDNDEGLQE AAVKMVVELA RLVSVISPLG DPQPHLTCLA HIVSLEPLAR
PAARARQWLP DFRIAGGRAA VLPGACWLGP FFNISPIPDD VRGAPQQEPS VLSQCFVGME
SRRPGDVNNA INTLRMAMKN IVGQLHGSVK SLLKLKTTKG HMVKWLGGVL EGNAGRSKMS
FTPESVAPDG FMVNVAAVLL KLCGPFMDTS PASPFWKRVD PGFVAHSHGL LDASYANETK
LAAASDEEAA WRERVRSNGA ASTASSEPSS PTGEGEGHHF ICQAFFLTAH ALHIGPIRSM
TMIEEDLARE MRWFAGAVQQ MEAAAAGSSN PMERAVIEQR LNQLRAQQDY VKARYNAFVA
TVLDPALITD VLAFYRLMAA WLMRVANRGA AGGVGGINIP LPEPAPEEFT CMPEYFVEDM
ANVLLFVGRS APQLLSSAAD GAGVRLEEFA VFFTSLMASP KHIRSSFLRS KLSEVLEQWL
PQTEEEDGRG GNFRRRAPSG ASADLAALFN CNPLVIQHLT PVLVQLYNDI EHTERSGAFY
FKFSMRVTIA NILKYLWAQP QHRAVWLAWV RSENYRGNSE KFASMLINDL TYLLDEVVRL
LKLLRQAEET RADEAKWAAM SQQERQEHES QAQFNGQNLT ALVRSANSVI STLNFVTEEL
DTTRTFLQPH MVTRLRDSLN YFLKYLVGPE RRQLRVKDQE KYGFNPRELL RGLVMVYLHV
ESIDRANPGP EGPVFAAAVG QDSRSFDAAY FDEASLVLDS GGLLNVGQRE QLASLAQRAL
AASTEAEAED EEMGEDVPEE FSCAILSTIM KDPVKLPSGV VVDRPNIQRH LLSDPTDPFS
RQPLTEDQLE PLPELTARIT AWRKQRSGAG K
//
