ID A0A2K3DJ87_CHLRE Unreviewed; 736 AA.
AC A0A2K3DJ87;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN ORFNames=CHLRE_07g324050v5 {ECO:0000313|EMBL:PNW80590.1};
OS Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX NCBI_TaxID=3055 {ECO:0000313|EMBL:PNW80590.1, ECO:0000313|Proteomes:UP000006906};
RN [1] {ECO:0000313|EMBL:PNW80590.1, ECO:0000313|Proteomes:UP000006906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-503 {ECO:0000313|Proteomes:UP000006906};
RX PubMed=17932292; DOI=10.1126/science.1143609;
RA Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.,
RA Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT "The Chlamydomonas genome reveals the evolution of key animal and plant
RT functions.";
RL Science 318:245-250(2007).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; CM008968; PNW80590.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K3DJ87; -.
DR STRING; 3055.A0A2K3DJ87; -.
DR PaxDb; 3055-EDP07131; -.
DR EnsemblPlants; PNW80590; PNW80590; CHLRE_07g324050v5.
DR Gramene; PNW80590; PNW80590; CHLRE_07g324050v5.
DR InParanoid; A0A2K3DJ87; -.
DR OMA; MFKDMTI; -.
DR OrthoDB; 21270at2759; -.
DR Proteomes; UP000006906; Chromosome 7.
DR ExpressionAtlas; A0A2K3DJ87; baseline.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF168; CULLIN-3; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006906}.
FT DOMAIN 372..605
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 736 AA; 84769 MW; 6DD0F5122235B893 CRC64;
MKKGPIKIEP FRHPVTVDPQ YADKTWKVLE DAIREIHNQN ASGLSFEELY RNAYNMVLHK
YGPRLYEGLI RTLTAHLTEV AKKIEEKEGA PFLRELKKRW DEHTKSSQMI RDILMYMDRT
FVVQQQKTPV FTLGLELWRD VVVRNRAISE RLLAIVSSLI MKERQGEVIE RGLIKSVTQM
LGELGHAVYV EDFEKPFLAA AAEFYRKEAQ EYITSSDCPE YLRKAEARLG EEAERCGAYL
DANSTEPKIT RVVETELLKA QMTPLLEMEH SGLIALMRDD KFDDLSRLYC LMRRVDNGLG
TVRHMLCEHV KEVGRALVSD PERSKDPVEY VQALLDMRDK YERIITQAFA DDKTFRNALN
QAFEHFVNLN VRSPEFISLF IDDKLRRGIK GLSDTDVEGV LDKVMALFRY LQEKDVFEKY
YKQHLAKRLL SGRTTSDDAE RNLLVKLKTE CGYQFTSKLE SMFTDIKTSR DTMNEFRTRL
VETGKLEAEL GGIDLQVQVL TTGSWPTQAP SKCNLPRELE AACESFRNFY LSTHSGRRLT
FQPNMGTADL RAVFGAGRRH ELNVSTYQMC VLLLFNEADS LSYRDIAQAT EIPAPDLKRA
LQSLACVKGR NVLRKEPAGK DVADSDVFFY NDKFTSKLIK VKISTVAATK EGESEKAETR
QKVEEDRKPQ IEAAIVRIMK ARQRLDHNTI ITEVTRQLQA RFVPNPATIK KRIESLIERE
FLARDEADRK FYTYVA
//
