ID A0A2K3NPM4_TRIPR Unreviewed; 727 AA.
AC A0A2K3NPM4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Niemann-pick C1-like protein {ECO:0000313|EMBL:PNY04985.1};
DE Flags: Fragment;
GN ORFNames=L195_g001419 {ECO:0000313|EMBL:PNY04985.1};
OS Trifolium pratense (Red clover).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Trifolium.
OX NCBI_TaxID=57577 {ECO:0000313|EMBL:PNY04985.1, ECO:0000313|Proteomes:UP000236291};
RN [1] {ECO:0000313|EMBL:PNY04985.1, ECO:0000313|Proteomes:UP000236291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Tatra {ECO:0000313|Proteomes:UP000236291};
RC TISSUE=Young leaves {ECO:0000313|EMBL:PNY04985.1};
RX PubMed=24500806; DOI=10.3732/ajb.1300340;
RA Istvanek J., Jaros M., Krenek A., Repkova J.;
RT "Genome assembly and annotation for red clover (Trifolium pratense;
RT Fabaceae).";
RL Am. J. Bot. 101:327-337(2014).
RN [2] {ECO:0000313|EMBL:PNY04985.1, ECO:0000313|Proteomes:UP000236291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Tatra {ECO:0000313|Proteomes:UP000236291};
RC TISSUE=Young leaves {ECO:0000313|EMBL:PNY04985.1};
RX PubMed=28382043; DOI=10.3389/fpls.2017.00367;
RA Istvanek J., Dluhosova J., Dluhos P., Patkova L., Nedelnik J., Repkova J.;
RT "Gene Classification and Mining of Molecular Markers Useful in Red Clover
RT (Trifolium pratense) Breeding.";
RL Front. Plant Sci. 8:367-367(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNY04985.1}.
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DR EMBL; ASHM01000575; PNY04985.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K3NPM4; -.
DR STRING; 57577.A0A2K3NPM4; -.
DR Proteomes; UP000236291; Unassembled WGS sequence.
DR ExpressionAtlas; A0A2K3NPM4; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR45727; NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1; 1.
DR PANTHER; PTHR45727:SF8; PATCHED FAMILY PROTEIN; 1.
DR Pfam; PF12349; Sterol-sensing; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000236291};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 295..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 473..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 284..424
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:PNY04985.1"
SQ SEQUENCE 727 AA; 80147 MW; 644A9E732AE019A4 CRC64;
LILATIPESE HGKPPSIITE DNIELLFEIQ EKVDGIRANY SGLFVSLSDI CLKPLGDDCA
TQSILQYFQM DPDNYDNYGG VEHAEYCFQH YTSTETCFSA FKAPLEPTTA LGGFSGNNYS
EASAFIITYP VNNALTKFGD ENGKAIAWEK AFIQLAKDEL LPMVQSSNLT LSFSAESSIE
EELKRESTAD IITILVSYIV MFAYISVTLG DTPHHLSSFY LSTKDQLADQ LNLPQTQIPW
FIDLWSKLKV SDQFTLLHSP LVRRRNTRDC LFEVAVALTT APETVLRLDG NQTRVLLGLS
GVLLVMLSVL GSVGFFSALG IKSTLIIMEV IPFLVLAVGV DNMCIIVDAV KRQPSDLPIE
EQISNALGEV GPSITLASLS EILAFAVGSF VSMPACRVFS MIAALAVLLD FILQITAFVA
LVTLDSVRAK DNRIDCFPCI KLNRYSLEQT EGIRQETDGL VTRYMKEVHA PFLGLWGVKI
LVIAIFGAFT LASIALCTRI EPGLEQQIAL PRDSYLQGYF SNISEYLRVG PPLYFVVKDY
NYSLESKHTN QLCSISHCDS NSLLNEISRA ALAPESSYIA KPAASWLDDF LVWISPEAFS
CCRKFTNDSY CPPDDQPPCC FPDEEPCGLG GVCKDCTTCF RHSDLVNDRP STAQFKEKLP
WFLDALPSAD CAKGGHGAYT NSLDLSASDA SAIQRPCHHF IPPFFPFSSS SSSSLMSMVE
TEHSERN
//
