ID A0A2K3NZ20_TRIPR Unreviewed; 994 AA.
AC A0A2K3NZ20;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=ATP-dependent DNA ligase {ECO:0000313|EMBL:PNY08263.1};
GN ORFNames=L195_g004779 {ECO:0000313|EMBL:PNY08263.1};
OS Trifolium pratense (Red clover).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Trifolium.
OX NCBI_TaxID=57577 {ECO:0000313|EMBL:PNY08263.1, ECO:0000313|Proteomes:UP000236291};
RN [1] {ECO:0000313|EMBL:PNY08263.1, ECO:0000313|Proteomes:UP000236291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Tatra {ECO:0000313|Proteomes:UP000236291};
RC TISSUE=Young leaves {ECO:0000313|EMBL:PNY08263.1};
RX PubMed=24500806; DOI=10.3732/ajb.1300340;
RA Istvanek J., Jaros M., Krenek A., Repkova J.;
RT "Genome assembly and annotation for red clover (Trifolium pratense;
RT Fabaceae).";
RL Am. J. Bot. 101:327-337(2014).
RN [2] {ECO:0000313|EMBL:PNY08263.1, ECO:0000313|Proteomes:UP000236291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Tatra {ECO:0000313|Proteomes:UP000236291};
RC TISSUE=Young leaves {ECO:0000313|EMBL:PNY08263.1};
RX PubMed=28382043; DOI=10.3389/fpls.2017.00367;
RA Istvanek J., Dluhosova J., Dluhos P., Patkova L., Nedelnik J., Repkova J.;
RT "Gene Classification and Mining of Molecular Markers Useful in Red Clover
RT (Trifolium pratense) Breeding.";
RL Front. Plant Sci. 8:367-367(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA repair metallo-beta-lactamase (DRMBL)
CC family. {ECO:0000256|ARBA:ARBA00010304}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNY08263.1}.
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DR EMBL; ASHM01002395; PNY08263.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K3NZ20; -.
DR STRING; 57577.A0A2K3NZ20; -.
DR Proteomes; UP000236291; Unassembled WGS sequence.
DR ExpressionAtlas; A0A2K3NZ20; baseline.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd16273; SNM1A-1C-like_MBL-fold; 1.
DR Gene3D; 3.40.50.12650; -; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR011084; DRMBL.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR23240; DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED; 1.
DR PANTHER; PTHR23240:SF35; DNA REPAIR METALLO-BETA-LACTAMASE FAMILY PROTEIN-RELATED; 1.
DR Pfam; PF04675; DNA_ligase_A_N; 1.
DR Pfam; PF07522; DRMBL; 1.
DR SUPFAM; SSF117018; ATP-dependent DNA ligase DNA-binding domain; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:PNY08263.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000236291}.
FT DOMAIN 262..363
FT /note="DNA repair metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF07522"
FT DOMAIN 768..962
FT /note="DNA ligase ATP-dependent N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04675"
FT REGION 411..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 517..608
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..437
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..556
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..598
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 994 AA; 111092 MW; 1E7861F6F2C67699 CRC64;
MASKSKSQTL DLNSTQLFTT ALQSLNLPKP SLPLPPLPSS SIPHSNLIPN TRFLIDAFRY
SGDFSVSYFL SHFHSDHYAG LTSSWSNGII FCSPITAHLL INILNIPSSF IYPLNLHQSV
TIDGSVITLI DANHCPGAVQ FLFQVPFMDQ SLRYVHTGDF RFSNEMMLDS ALGCFIGADA
VFLDTTYCHP KFVFPTQDES VNYVVDVVNQ CDGDDVLFLV ATYVVGKEKI LLEIAKRFGK
KVHVDARKME VLRALGYGES GQFTEDSLET NIHVVGWNVL GETWPYFRPN FVKMKEIMTE
RGYSKVVGFV PTGWTYEVKR DKFAVRSKDS CRIHLVPYSE HSNYDELREY VRFLKPKSVV
PTVGLDVEKS DSKHVDKMRK YFAGLVDETA NKKEFLRGFK QCDSSEVGLE AGKDVSDDLE
PGKSIEKEVK PSDAGEDKNI NPDVAVSVSS CMGETFIEDP TLLNDEEKEK VIQELSCCLP
TWVTRSQMLD LISISGSNIV EAVSNFFERE TEFHEQVNSA QTSVPTPRCC SSNDTSTSPI
SKSNLNDTNG TLKKCDIFPS QDSKMVNLRP PLRNQISPSK RKRSSETKPN KKGKVKVQAK
SESSGSKQAT ITKFFSKAMP VMPGDTQSDQ LGSKPDESPI VEELLPTDAG NLYKQEIDQF
MQIINGDESL KKQVITIIEN TKGDINKALD IYYCNGCNLG GKEIAVQGEC KIDRPLENKC
VSQELKVIPD ISMHRMLKDN VDSTHVSLPS EKYNPKNHAC WRDGEPAPYL HLARTFNLLE
DEKGKIKATS ILCNMFRSLL ALSPEDVLPA VYLCTNKIAA DHENVELNIG GSLVTTALEE
ACGTNRLKLK EMYNKLGDLG DVAQECRQTQ RLLAPPTPLL IKDIYSALRK IRFKMNPRCG
SNFSFTLDYL NYKCNGSTLR KKGIIVHLMR SCREKEIKFL VRTLVRNLRI GAMLRTVLPA
LAHAVVMNSR PTVCQEGKAE NLKAALQRSR GASI
//
