ID   A0A2K3QGM6_9HYPO        Unreviewed;       536 AA.
AC   A0A2K3QGM6;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Magnesium transporter NIPA8 {ECO:0000313|EMBL:PNY26692.1};
GN   ORFNames=TCAP_03370 {ECO:0000313|EMBL:PNY26692.1};
OS   Tolypocladium capitatum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Tolypocladium.
OX   NCBI_TaxID=45235 {ECO:0000313|EMBL:PNY26692.1, ECO:0000313|Proteomes:UP000236621};
RN   [1] {ECO:0000313|EMBL:PNY26692.1, ECO:0000313|Proteomes:UP000236621}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 113982 {ECO:0000313|EMBL:PNY26692.1,
RC   ECO:0000313|Proteomes:UP000236621};
RA   Quandt C.A., Patterson W., Spatafora J.W.;
RT   "Harnessing the power of phylogenomics to disentangle the directionality
RT   and signatures of interkingdom host jumping in the parasitic fungal genus
RT   Tolypocladium.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PNY26692.1}.
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DR   EMBL; NRSZ01000511; PNY26692.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2K3QGM6; -.
DR   OrthoDB; 1384258at2759; -.
DR   Proteomes; UP000236621; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.3730.20; -; 1.
DR   InterPro; IPR008521; Mg_trans_NIPA.
DR   PANTHER; PTHR12570:SF9; MAGNESIUM TRANSPORTER NIPA8-RELATED; 1.
DR   PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR   Pfam; PF05653; Mg_trans_NIPA; 1.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000236621};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        112..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        153..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        228..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        260..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        286..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          347..375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          393..474
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          488..536
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        361..375
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        488..503
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   536 AA;  57683 MW;  46E0635C39C513B7 CRC64;
     MGSLGGLSPG GSIALGILVG LMSTSVQSLG LTLQRKSHIL EDEKGPQDER RPPYRRRRWQ
     LGMGMFIIAN LLGSTVQIST LPLPVLSTLQ AAGLVFNSIC ATLILSEPFT RWSLCGTVLV
     TTGAILIAIF GAIPSPAHDL NELLELLARR PFIAWMILQA LFVVAVAVVI EVVNKTSSVS
     HNSQFRLARG ITYGIISGDL SAHALLFAKS AVELLIKTIG GKNQFTHWQS WAIVLALVAL
     ALCQLYYLHR GLKLVSTSVL YPLVFCVYNI IAILDGLIYF NQTSLISALR ACVIALGTVI
     LLTGVMALSW RLSDEQHAPG VGQSTLAPGL GLVDDTEGEE ESLLGSEAAV EEEETPTYHT
     FPAVNGETTP LTPTRKKSFR WAERAEIWGE LQDQEEPTTP TCRLRPNTLP GRTEVSPLLP
     PARRSVRGVA PTDEAGPSTE STPRKFGRRR RKSTGFPGLV ARRSIRRRGP SASGSLRTFL
     SLGWWTNRGN RSSISSSGAV DSLSRPRLSD DAADDDGRSG GESGGGGGSR RDDSAV
//