ID A0A2K3QMJ5_9HYPO Unreviewed; 1512 AA.
AC A0A2K3QMJ5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=ABC transporter CDR4 {ECO:0000313|EMBL:PNY28748.1};
GN ORFNames=TCAP_01327 {ECO:0000313|EMBL:PNY28748.1};
OS Tolypocladium capitatum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Tolypocladium.
OX NCBI_TaxID=45235 {ECO:0000313|EMBL:PNY28748.1, ECO:0000313|Proteomes:UP000236621};
RN [1] {ECO:0000313|EMBL:PNY28748.1, ECO:0000313|Proteomes:UP000236621}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 113982 {ECO:0000313|EMBL:PNY28748.1,
RC ECO:0000313|Proteomes:UP000236621};
RA Quandt C.A., Patterson W., Spatafora J.W.;
RT "Harnessing the power of phylogenomics to disentangle the directionality
RT and signatures of interkingdom host jumping in the parasitic fungal genus
RT Tolypocladium.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNY28748.1}.
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DR EMBL; NRSZ01000216; PNY28748.1; -; Genomic_DNA.
DR STRING; 45235.A0A2K3QMJ5; -.
DR OrthoDB; 5473955at2759; -.
DR Proteomes; UP000236621; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010929; PDR_CDR_ABC.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR PANTHER; PTHR19241:SF625; ATP-DEPENDENT PERMEASE PDR10-RELATED; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF06422; PDR_CDR; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000236621};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 522..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 554..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 596..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..653
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 659..681
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 779..799
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1203..1224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1275..1303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1324..1345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1357..1378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1476..1497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 160..409
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 865..1108
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 37..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1512 AA; 167984 MW; AB076D3B2B72192D CRC64;
MYGINTNYDG TAATTGVPIT TRHGARDQHV VHVSAPATSL TEAGNDDDGA KDDSSAVTET
DMAHRSSVVQ ALARSYSRTS AASPGQNPFL AGPDSLLNPS SPNFSGREWA KAIVELVSHD
GATFRSAGVC FQDLNVHGYG APTDYQKNVA NVWLSAAGLV RTLTGSSSRQ RIDILRDFDG
LVQKGEMLVV LGPPGSGCST FLKTIAGEMN GLYVDDGSYF NYQGITAKEM HSQHRGEAIY
TAEVDVHFPQ LTVGDTLTFA AMARQPRTLP LGLDGEKFAA HLRDVVMAMF GISHTVNTRV
GNEFVRGVSG GERKRVTISE AALSGAPLQC WDNSTRGLDS ANAVEFCRTL RLQTELFDST
ACVSIYQAPQ SAYDLFDKAV VLYEGRQIFF GRADAAKQYF VNLGFDCPAR QTTPDFLTSM
TSPLERVVRP GFEGKVPRTP DEFAVAWKSS AERKALQAEI EDYNTAHPIN GPDAEAFRAS
RQAQQAKGQR RRSPYTLSYA QQVRLCLWRG WRRLIGDPSI SLGALIGNFI MALIIGSCFY
NLEDTSSSFF QRGALLFFAC LMNAFASSLE ILTLYAQRPI VEKHSRYALY HPSAEAVSSM
LCDLPYKIAN CIVFNLTVYF MTNLRREPGA FFFFVLITFA TVMVMSMIFR TIGSASRTLF
QALVPAAILI LDLVIFTGFI LPSRYMLGWC RWLSYLNPLG YSFEAIMVNE FHDREFRCTQ
YVPTSDAPSP SVATTLAKYA NVAAVNQVCA AVGAVPGDKF VNGDVYVRSQ FGYEWDHRWR
NLGIVIAFTL ALLFSYIVGA ELVSEAKSRG EVLVYRRGHK PAAARHAEKK QRDPEAAMAN
IGPILSTDRS RGKEGGMLQQ QTSVFQWHDV CYDVKIKGET RRILDHVDGW VKPGTLTALM
GVSGAGKTTL LDCLADRTSM GVITGEMLVD GMPRDMSFQR KTGYVQQQDL HLQTTTVREA
LNFSAILRQP AHVPREEKLA YVDEVIKLLE MEEYADAVVG VPGEGLNVEQ RKRLTIGVEL
AAKPPLLLFV DEPTSGLDSQ TSWAILDLLE KLTKAGQAVL CTIHQPSAML FQRFDRLLFL
AKGGKTVYYG EIGENSKTMT SYFERNGGHP CPDAANPAEW MLEVIGAAPG SSTDVDWFDT
WRNSQEYRDV QAELETIKRE KRGVTSNPIA EDPGSYHEFA APFMLQLKEN LFRVFQQYWR
TPVYIYAKMA LCTLVPLFVG FIFFRTPNSI QGLQSQMFSI FQLLTIFIQI VQQSMPQFVI
QRSLFEARER PSKVYSWKVF MLSQIIVELP WNGLMSVIMY FGWYYPLGLY RNAIPTDAVT
ERGALMFLFL FIFMIFTGTF SAFVIAGVET AEGGGNLANL LFTMSLMFCG VLIQPDALPR
FWIFMYRVSP LTYLVNGMLS VAVSGTNVVC ADNELLHMEP PSNQTCGEYM SSYIDVFGGL
MTNAHATTDC AFCPIADTDK FLAGVGSYYD QRWRSFGIVL VYIFFNIGAA LFIYWLARVP
KKSMGKGKKK KE
//
