ID A0A2K3V2D7_9DEIO Unreviewed; 360 AA.
AC A0A2K3V2D7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=2-dehydropantoate 2-reductase {ECO:0000313|EMBL:PNY82946.1};
GN ORFNames=CVO96_08755 {ECO:0000313|EMBL:PNY82946.1};
OS Deinococcus koreensis.
OC Bacteria; Deinococcota; Deinococci; Deinococcales; Deinococcaceae;
OC Deinococcus.
OX NCBI_TaxID=2054903 {ECO:0000313|EMBL:PNY82946.1, ECO:0000313|Proteomes:UP000236379};
RN [1] {ECO:0000313|EMBL:PNY82946.1, ECO:0000313|Proteomes:UP000236379}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SJW1-2 {ECO:0000313|EMBL:PNY82946.1,
RC ECO:0000313|Proteomes:UP000236379};
RA Choi A.;
RT "Deinococcus koreensis sp. nov., a radiation-resistant bacterium isolated
RT from river water.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ketopantoate reductase family.
CC {ECO:0000256|ARBA:ARBA00007870}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNY82946.1}.
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DR EMBL; PPPD01000001; PNY82946.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K3V2D7; -.
DR OrthoDB; 9793586at2; -.
DR Proteomes; UP000236379; Unassembled WGS sequence.
DR GO; GO:0008677; F:2-dehydropantoate 2-reductase activity; IEA:InterPro.
DR GO; GO:0015940; P:pantothenate biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR003710; ApbA.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR NCBIfam; TIGR00745; apbA_panE; 1.
DR PANTHER; PTHR21708:SF26; 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000236379}.
FT DOMAIN 11..156
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 185..326
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 360 AA; 37657 MW; FF536D5CE2780FFB CRC64;
MDEGEDTQQR VLIWGAGAIG GAIGAALIRS GVDVTFVDVA QAHVQAIRER GLQVTGPFGG
PTVRASACTP EELAGQWPLA LLCTKAQDTR AAGEALRPHV TGDGAVVSVQ NGLNPLILNE
ILGPGRVLGA FVNFGADYLE PGVVTYGGRG AVVVGEQGGA LTARAHAIHA LLQRFEPAAI
LTPNIFGYLW SKLGYGSLLF ATAVTDDSIA DALARPDNRA MYVELGREVM RVALAHGVTP
EAFNGFDPAA FLPGAGDAQA HASLDDLVAF NRRSAKTHSG IWRDLAVRKR RTEVDAQVGW
VVHFGDQHGV PTPLNALLVE LIHDIENGRR TLDAAGTDGP NMRALRAAMP AISGVPGVGA
//
