ID A0A2K4ZHM7_9FIRM Unreviewed; 398 AA.
AC A0A2K4ZHM7;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Transposase from transposon Tn916 {ECO:0000313|EMBL:SOY29965.1};
GN Name=Int-Tn_3 {ECO:0000313|EMBL:SOY29965.1};
GN ORFNames=AMURIS_02686 {ECO:0000313|EMBL:SOY29965.1};
OS Acetatifactor muris.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Acetatifactor.
OX NCBI_TaxID=879566 {ECO:0000313|EMBL:SOY29965.1, ECO:0000313|Proteomes:UP000236311};
RN [1] {ECO:0000313|EMBL:SOY29965.1, ECO:0000313|Proteomes:UP000236311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GP69 {ECO:0000313|EMBL:SOY29965.1};
RA Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
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DR EMBL; OFSM01000013; SOY29965.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K4ZHM7; -.
DR OrthoDB; 9803188at2; -.
DR Proteomes; UP000236311; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008907; F:integrase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR CDD; cd01189; INT_ICEBs1_C_like; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004191; Integrase_Tn916-type_DNA-bd_N.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR Pfam; PF02920; Integrase_DNA; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00023195};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000236311};
KW Viral genome integration {ECO:0000256|ARBA:ARBA00023195};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 79..163
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 186..393
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 398 AA; 45585 MW; 045FAB0E061FB468 CRC64;
MSEKRRDNRN RILRSGESQR KDGRYAYKYT DTFGKVQFVY AWKLVPTDKT PAGKRDDISL
REKEKEIQKD LDDGIDTIGK KMTVCELYAK QNRHRGNVRH NTTKGRERLM KLLEADKLGS
CPIDSVKLSD AKEWALRMKE KGISYKTISN DKRSLKAAFY TAIQDDCIRK NPFDFQLNTV
IEDDTEPKVP LTAEQEESLL SFMESDSVYQ KYRDEVIILL GTGLRISELC GLTDTDLDFE
SRVINVDHQL LRSAETGYYI EKPKTQSGIR QIPMSEKVYE ALGRVLENRK GAKATTIDGY
SNFLFLNRDG CPKTATSYDN MFRGLAKKYN KCHEEALPKV MTPHTLRHTF CTNLANAGMN
PKALQYIMGH SNITMTLNYY AHATFASARA EMERLIAA
//
