ID A0A2K5ATV3_CAEEL Unreviewed; 861 AA.
AC A0A2K5ATV3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Tudor domain-containing protein {ECO:0000313|EMBL:SPC47538.1};
GN Name=akap-1 {ECO:0000313|EMBL:SPC47538.1,
GN ECO:0000313|WormBase:C56G2.1d};
GN ORFNames=C56G2.1 {ECO:0000313|WormBase:C56G2.1d}, CELE_C56G2.1
GN {ECO:0000313|EMBL:SPC47538.1};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:SPC47538.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:SPC47538.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:SPC47538.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284603; SPC47538.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K5ATV3; -.
DR SMR; A0A2K5ATV3; -.
DR EnsemblMetazoa; C56G2.1d.1; C56G2.1d.1; WBGene00016977.
DR AGR; WB:WBGene00016977; -.
DR WormBase; C56G2.1d; CE52511; WBGene00016977; akap-1.
DR OrthoDB; 4118571at2759; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00016977; Expressed in larva and 5 other cell types or tissues.
DR ExpressionAtlas; A0A2K5ATV3; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22395; KH-I_AKAP1; 1.
DR CDD; cd20407; Tudor_AKAP1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.40.50.90; -; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR InterPro; IPR047368; KH-I_AKAP1.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR047367; Tudor_AKAP1.
DR PANTHER; PTHR22948:SF65; A-KINASE ANCHOR PROTEIN 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR22948; TUDOR DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF00567; TUDOR; 1.
DR SMART; SM00322; KH; 1.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
DR PROSITE; PS50304; TUDOR; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|EPD:A0A2K5ATV3,
KW ECO:0007829|PeptideAtlas:A0A2K5ATV3};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 108..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 683..741
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 145..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 475..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..275
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..308
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..373
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..390
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..452
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..504
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 861 AA; 95717 MW; 8FE76E3BE99B744D CRC64;
MVAAAAADAL AAGGDSSSPS DLYNKITGQQ SSTTTSLSYA ACDVITRHLI SMLLEISNWT
NDLAKYLAGS EQSSDDGHNE RCLLFSSIFF AIDPSLALAQ MSSVASKHAL LIALGGFSIA
ALFVWYINKK DKDGRKKKKV GDVISNGLPK TATASDVQTE NGNVKKANGH VNGDVQSSIG
VSQKQQQKDE DEKTQKKDAV QNEKPSIDKK QPKSQAPTEK KEEKTVEIHT ETEETDHVAA
GDSGVVSEHK EHDKKTKQKN DEPVSIDKKS EEIEVPKQAG VVNEEPKKQS EETVVEEQFV
KKEEPKLKSA PTPLLTMPSK KKIPEEPTPT KMNDATSPLS LDIAAQMSPA SFSWSEEMEK
SFNEEEFRLN ESSDIDRSPA SPLRHLQQQH NKNRSSQKRK GGRVNGRDGV HQPQQQHQQQ
KKEEQGQIKK GQRRLTKEKS VEETPEKSQK RVVLKHHENE AGDAAHAQII ESPHHENASY
EKSDSPGLDS QNSEASSQDS GRATGPLASP HEDGLTTEDD FLPMYEFEIP NSLVGLIIGV
KGKTIKELSV RTNVRMLIRQ HHETDKVKTH QICQVRGKRD EINHCLQMLR RRFPPARFPE
LNLQPVVPPV LPNSNFDMLS TQPTWLTLPE DIKCEVAVSS IISASHFFIQ QPTHPSFASL
RHLDMYMGSL YGEQSNLPEL PIPCQNGLLC AAPVGNAWFR AVTVQYFDET DEVFVKFVDY
GGYSKMARQD LRQIRTDLMS LPFQSTEVML AHVRPVDGTT NWSDAAMQKF RAMCIGKVIN
CKMVGQSHDT RIPMVELYMM SKDGKDAQEV RFDQVLMNCG LARTADPSKM SRITVPAALD
TESRMKRPSF SSQTSQTAVV C
//
