ID A0A2K5BYU4_AOTNA Unreviewed; 1083 AA.
AC A0A2K5BYU4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=LIM and calponin homology domains 1 {ECO:0000313|Ensembl:ENSANAP00000001599.1};
GN Name=LIMCH1 {ECO:0000313|Ensembl:ENSANAP00000001599.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000001599.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000001599.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5BYU4; -.
DR Ensembl; ENSANAT00000014728.1; ENSANAP00000001599.1; ENSANAG00000004850.1.
DR GeneTree; ENSGT00950000183159; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0031032; P:actomyosin structure organization; IEA:InterPro.
DR CDD; cd21278; CH_LIMCH1; 1.
DR CDD; cd08368; LIM; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR InterPro; IPR001997; Calponin/LIMCH1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR031865; DUF4757.
DR InterPro; IPR003096; SM22_calponin.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR15551:SF3; LIM AND CALPONIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR15551; LIM DOMAIN ONLY 7; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF15949; DUF4757; 1.
DR Pfam; PF00412; LIM; 1.
DR PRINTS; PR00889; CALPONIN.
DR PRINTS; PR00888; SM22CALPONIN.
DR SMART; SM00033; CH; 1.
DR SMART; SM00132; LIM; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 21..125
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 1011..1077
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 185..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 614..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 681..704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 741..762
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 833..1006
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 354..439
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 782..823
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 185..206
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..256
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..633
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 686..702
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 741..760
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 833..853
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 860..896
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..951
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 970..984
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1083 AA; 122096 MW; ECD55EA788B5D1D1 CRC64;
MACPALGLEA LQPLQPEPPP EPAFSEAQKW IEQVTGRSFG DKDFRTGLEN GILLCELLNA
IKPGLVKKIN RLPTPIAGLD NIILFLRGCK ELGLKESQLF DPNDLQDTSN RVTVKSLDYS
RKLKNVLVTI YWLGKAANSC TSYSGTTLNL KEFEGLLAQM RKETDDIESP KRSIRDSGYI
DCWDSERSDS LSPPRHGRDD SFDSLDSFGS RSRQTPSPDV VLRGSSDGRG SDSESDLPHR
KLPDVKKDDM SARRTSHGEP KSVVPFNQYL PNKSNQTAYV PAPLRKKKAE REEYRKSWST
ATSPLGGERP FRYGPRTPVS DDAESTSMFD MRCEEEAAVQ PHSRARQEQL QLINNQLREE
DDKWQDDLAR WKSRRRSVSQ DLIKKEEERK KMEKLLAGED RTSERRKSIK TYREIVQEKE
RRERELHEAY KNARSQEEAE GILQQYIERF TISEAVLERL EMPKILERSH STEPNLSSFL
NDPNPMKYLR QQSLPPPKFT ATVETTIARA SVLDTSMSAG SGSPSKTVTP KAVPMLTPKP
YSQPKNSQEV LKTFKVDGKV SMNGETVHRE EERERECPAV APAHSLTKSQ MFEGVARVHG
SPLELKQDNS SIEINIKKPN SVSQELTATT EKTEPNSQED ENDGGKPSKG NIELATSEPQ
HFTTTVTRCS PTVAFVEFPS SSQLKNDVPE EKDQKKQENE MSGKVELVLS QKVVKPKSPE
PEATLTFPFL DKMPEANQLH LPNLSSQVDS PSSEKSPVTT PQFKFWAWDP EEERRRQEKW
QQEQERLLQE RYQKEQDKLK EEWEKAQKEV EEEERRYYEE ERKIIEDTVV PFTISSSSAD
QLSTSSSVTE GSGAMNKIDL ENCQDEKQDR RWKKSFQGDD NDLLLKTRES DRLEEKGSLT
QGALVHSGNP VSKGVHEDHQ LDTEAGAPHC GTNPQLAQDP SQNQQVSNPM HSAEDVKPKT
LPLDKSINHQ IESPGERRKK SPRENFQAGP FSPCSPTPPG QSPNRSISGK KLCSSCGLPL
GKGAAMIIET LNLYFHIQCF RCGICKGQLG DAVSGTDVRI RNGLLNCNDC YMRSRSAGQP
TTL
//
