ID   A0A2K5C152_AOTNA        Unreviewed;       687 AA.
AC   A0A2K5C152;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Kelch like family member 1 {ECO:0000313|Ensembl:ENSANAP00000002426.1};
GN   Name=KLHL1 {ECO:0000313|Ensembl:ENSANAP00000002426.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000002426.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000002426.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K5C152; -.
DR   STRING; 37293.ENSANAP00000002426; -.
DR   Ensembl; ENSANAT00000019345.1; ENSANAP00000002426.1; ENSANAG00000018250.1.
DR   GeneTree; ENSGT00940000160425; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   GO; GO:0030425; C:dendrite; IEA:Ensembl.
DR   GO; GO:0043025; C:neuronal cell body; IEA:Ensembl.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Ensembl.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   CDD; cd18509; BACK_KLHL1; 1.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR24412:SF35; ACTIN-BINDING PROTEIN IPP; 1.
DR   PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 6.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 6.
DR   SUPFAM; SSF117281; Kelch motif; 2.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          165..218
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
FT   REGION          22..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        45..92
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   687 AA;  75806 MW;  899A44F961884BD0 CRC64;
     MSGSGRKDFD VKHILRLRWK LFSHPSPSTG GPAGGGCLQQ DGSGSFEHWG PSQSRLLKSQ
     ERSGVSTFWK KPSSSSSSSS SPSSSSSSFN PLNGTLLPVA TRLQQGTPGQ GSQQPARTLF
     YVESLEEEVV PGMDFPGPHE KGLVLQELKV EPDNSSQATG EGCGHRLVLS SVSDYFAAMF
     TSDVCEAKQE EIKMEGIDPN ALWDLVQFAY TGCLELKEDT IENLLAAACL LQLPQVVEVC
     CHFLMKLLHP SNCLGIRAFA DAQGCIELMK VAHSYTMENI MEVIRNQEFL LLPAEELHKL
     LASDDVNVPD EETIFHALMM WVKYDMQRRC NDLSMLLAFI RLPLLPPQIL ADLENHALFK
     NDLECQKLIL EAMKYHLLPE RRTLMQSPRT KPRKSTVGTL YAVGGMDNNK GATTIEKYDL
     RTNLWIQAGM MNGRRLQFGV AVIDDKLFVI GGRDGLKTLN TVECYNPKTK TWTVLPPMAT
     HRHGLGVTVL EGPIYAVGGH DGWSYLNTVE RWDPQSQQWT FVASMSIARS TVGVAALNGK
     LYSVGGRDGS SCLSSMEYYD PHTNKWNMCA PMCKRRGGVG VATCDGFLYA VGGHDAPASN
     HCSRLLDYVE RYDPKTDTWT MVAPLSMPRD AVGVCLLGDR LYAVGGYDGQ TYLNTMESYD
     PQTNEWTQMA SLNIGRAGAC VVVIKQP
//