ID A0A2K5C3L5_AOTNA Unreviewed; 651 AA.
AC A0A2K5C3L5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Galactosidase beta 1 like {ECO:0000313|Ensembl:ENSANAP00000003285.1};
GN Name=GLB1L {ECO:0000313|Ensembl:ENSANAP00000003285.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000003285.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000003285.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
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DR RefSeq; XP_012301344.1; XM_012445921.1.
DR RefSeq; XP_012301345.1; XM_012445922.1.
DR RefSeq; XP_012301347.1; XM_012445924.1.
DR AlphaFoldDB; A0A2K5C3L5; -.
DR STRING; 37293.ENSANAP00000003285; -.
DR Ensembl; ENSANAT00000020910.1; ENSANAP00000003285.1; ENSANAG00000019491.1.
DR GeneID; 105712739; -.
DR CTD; 79411; -.
DR GeneTree; ENSGT00950000182942; -.
DR OMA; HERQYLH; -.
DR OrthoDB; 5489808at2759; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR PANTHER; PTHR23421:SF50; BETA-GALACTOSIDASE-1-LIKE PROTEIN; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..651
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014411425"
FT DOMAIN 38..353
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 400..512
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 537..594
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 185
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 263
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 651 AA; 73664 MW; 9B6FF87A26321C11 CRC64;
MAPKKPSCLH SLLLPLLTLL LPQADTRSFV VDRDHDRFLL DGAPFRYVSG SLHYFRVPRV
LWADRLLKMR WSGLNTIQFY VPWNYHEPQP GVYNFNGSRD LIAFLNEAAL ANLLVILRPG
PYICAEWEMG GLPSWLLRKP EIHLRTSDPD FLAAVDSWFK VLLPKIYPWL YHNGGNIISI
QVENEYGSYR ACDSSYMRHL AGLFRALLGE KILLFTTDGP EGLQCGSLQG LYTTVDFGPA
DNMTKIFTLL RKYEPHGPLV NSEYYTGWLD YWGQNHSTQS VSAVTKGLEN MLELGASVNM
YMFHGGTNFG YWNGADKKGR FLPITTSYDY DAPISEAGDP TPKLFALRNV ISKFQEVPLG
PLPPPSPKMM LGPLTLHLVG HLLAFLDLLC PHGPINSILP MTFEAVKQDH GFMLYRTYLT
HTIFEPTPFW VPNNGVHDRA YVMVDGVFQG VLERNMRDKL FLMGKLGSKL DILLENMGRL
SFGSNSSDFK GLLEPPILGH TILTQWMMFP LKIDNLVKWW FPLQLLKRPH PQAPSGPTFY
SKTFPIVGSV GDTFLYLPGW TKGQVWINGF NLGRYWTTQG PQQTLYVPRF LLFPKGALNK
ITLLELENVP LQPQVQFLDK PILNSTLHGL RIDSLSADTL SASEPMELSG H
//
