ID A0A2K5C547_AOTNA Unreviewed; 342 AA.
AC A0A2K5C547;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Growth arrest specific 1 {ECO:0000313|Ensembl:ENSANAP00000003812.1};
GN Name=GAS1 {ECO:0000313|Ensembl:ENSANAP00000003812.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000003812.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000003812.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_012319067.1; XM_012463644.1.
DR AlphaFoldDB; A0A2K5C547; -.
DR STRING; 37293.ENSANAP00000003812; -.
DR Ensembl; ENSANAT00000021509.1; ENSANAP00000003812.1; ENSANAG00000019938.1.
DR GeneID; 105724828; -.
DR CTD; 2619; -.
DR GeneTree; ENSGT00390000001195; -.
DR OMA; NRYLTYC; -.
DR OrthoDB; 5323788at2759; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IEA:Ensembl.
DR GO; GO:0045930; P:negative regulation of mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0010955; P:negative regulation of protein processing; IEA:Ensembl.
DR GO; GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IEA:Ensembl.
DR InterPro; IPR039596; GAS1.
DR InterPro; IPR016017; GDNF/GAS1.
DR PANTHER; PTHR16840; GROWTH ARREST-SPECIFIC PROTEIN 1; 1.
DR PANTHER; PTHR16840:SF3; GROWTH ARREST-SPECIFIC PROTEIN 1; 1.
DR Pfam; PF02351; GDNF; 1.
DR SMART; SM00907; GDNF; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..342
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014439393"
FT DOMAIN 48..145
FT /note="GDNF/GAS1"
FT /evidence="ECO:0000259|SMART:SM00907"
FT DOMAIN 165..242
FT /note="GDNF/GAS1"
FT /evidence="ECO:0000259|SMART:SM00907"
FT REGION 253..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..289
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 342 AA; 35428 MW; 3A4A4369047CBF94 CRC64;
MVAALLGGGG EARGGTVPGA WLCLMALLQL LSSAPRGSGL AHGRRLICWQ ALLQCQGEPE
CSYAYNQYAE ACAPVLAQHD GGDAPGAAAA AFPASAASFS RWRCPSHCIS ALIQLNHTRR
GPALEDCDCA QDENCKSTKR AIEPCLPRTN GGGAGGPGAG GVMGCTEARR LCDRDSHCNL
ALSRYLAYCG KVFNGLRCTD ECRTVIDDML AMPKAALLND CVCDGLERPI CESVKENMAR
LCFGGELGNG PGSSGSDGGL DDYYDEDYDD EQRAPGGEQP LDDDDGVPHP PRPGSGAAAA
GGRGDLPYGP GRRSSGGGGR SAPLGTWTPL ASILLLLLGP LF
//
