ID A0A2K5C6E3_AOTNA Unreviewed; 335 AA.
AC A0A2K5C6E3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Milk fat globule EGF and factor V/VIII domain containing {ECO:0000313|Ensembl:ENSANAP00000004267.1};
GN Name=MFGE8 {ECO:0000313|Ensembl:ENSANAP00000004267.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000004267.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000004267.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; A0A2K5C6E3; -.
DR Ensembl; ENSANAT00000022014.1; ENSANAP00000004267.1; ENSANAG00000020190.1.
DR GeneTree; ENSGT00940000156049; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00057; FA58C; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 3.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR46806; F5/8 TYPE C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46806:SF5; F5_8 TYPE C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF00754; F5_F8_type_C; 2.
DR SMART; SM00181; EGF; 1.
DR SMART; SM00231; FA58C; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01285; FA58C_1; 1.
DR PROSITE; PS01286; FA58C_2; 1.
DR PROSITE; PS50022; FA58C_3; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..335
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014464509"
FT DOMAIN 23..67
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 70..225
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 230..291
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 292..335
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DISULFID 57..66
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 335 AA; 37675 MW; FBC8CD9ADA768CF7 CRC64;
MSRPRLLAAL CGALLCAPSL LVALDVCSKN PCHNNGLCKD IAQEVRGDVF PAYTCECLQG
YVGSHCELKC AEPLGMENGN IANSQITASS VRVTFLGVQH WVPELARLNR AGMVNAWTPS
SNDDSPWIQV NLLRRMWVAG VVTQGASRLA NHEYLKTFKV AYSLNGHDFD FIHDVNQKHK
EFTGNWNKNT VHINLFETPV EAQYVRLYPT SCHTACTLRF ELLGCELNGC HHPLGLKNNS
IPDKQITASS SYKTWGLHLF SWNPSYARLD KQGNFNAWVA GSYDKDQWLQ IFPGNWDNHS
HKKNVFETPV LARYVRVLPV AWHNRVALRL ELLGC
//
