ID   A0A2K5CBQ5_AOTNA        Unreviewed;      1138 AA.
AC   A0A2K5CBQ5;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Folliculin interacting protein 1 {ECO:0000313|Ensembl:ENSANAP00000006141.1};
GN   Name=FNIP1 {ECO:0000313|Ensembl:ENSANAP00000006141.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000006141.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000006141.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Lysosome membrane
CC       {ECO:0000256|ARBA:ARBA00004656}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004370}.
CC   -!- SIMILARITY: Belongs to the FNIP family.
CC       {ECO:0000256|ARBA:ARBA00007541}.
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DR   RefSeq; XP_012302901.1; XM_012447478.1.
DR   AlphaFoldDB; A0A2K5CBQ5; -.
DR   Ensembl; ENSANAT00000023905.1; ENSANAP00000006141.1; ENSANAG00000020977.1.
DR   GeneID; 105713621; -.
DR   CTD; 96459; -.
DR   GeneTree; ENSGT00390000009391; -.
DR   OrthoDB; 2725349at2759; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR037545; DENN_FNIP1/2.
DR   InterPro; IPR028086; FNIP_C_dom.
DR   InterPro; IPR026156; FNIP_fam.
DR   InterPro; IPR028085; FNIP_mid_dom.
DR   InterPro; IPR028084; FNIP_N_dom.
DR   PANTHER; PTHR21634:SF12; FOLLICULIN-INTERACTING PROTEIN 1; 1.
DR   PANTHER; PTHR21634; UNCHARACTERIZED; 1.
DR   Pfam; PF14638; FNIP_C; 1.
DR   Pfam; PF14637; FNIP_M; 1.
DR   Pfam; PF14636; FNIP_N; 1.
DR   PRINTS; PR02073; FOLLICULNIP1.
DR   PROSITE; PS51836; DENN_FNIP12; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT   DOMAIN          37..1129
FT                   /note="UDENN FNIP1/2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51836"
FT   REGION          754..785
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          884..928
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        754..775
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        884..902
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1138 AA;  127409 MW;  DF86BC1C17933022 CRC64;
     MAPTLFQKLF SKRSGLGAPG RDARDPDCGF SWPLPEFDPS QIRLIVYQDC ERRGRNVLFD
     SSVKRKNEDI SVSKLCSDAQ VKVFGKCCQL KPGGDSSSSL DSSVTSSSDV KDQCLKYQGS
     RCSSDANMLG EMMFGSVAMS YKGSTLKIHQ IRSPPQLMLS KVFTARTGSS ICGSLNTLQD
     SLEFINQDNN TLKADNNTVI NGLLGNIVHS NPMDMPGREL NEDRDSGIAR SASLSSLLIT
     PFPSPNSSLT RSCASSYQRR WRRSQTTSLE NGVFPRWSIE ESFNLSDESC GPNPGIVRKK
     KIAIGVIFSL SKDEDENNKF NEFFFSHFPL FESHMNKLKS AIEQAMKMSR RSADASQRSL
     AYNRIVDALN EFRTTICNLY TMPRIGEPVW LTMMSGTPEK NHLCHRFMKE FTFLMENASK
     NQFLPALITA VLTNHLAWVP TVMPNGQPPI KIFLEKHSSQ SVDMLAKTHP YNPLWAQLGD
     LYGAIGSPVR LARTVVVGKR QDMVQRLLYF LTYFIRCSEL QETHLLENGE DEAIVMPGTV
     ITTTLEKGEI EESEYVLVTM HRNKSSLLFK ESEEVRTPNC NCKYCSHPLL GQNVENISQQ
     EREDIQNSSK ELLGISDECQ MISPSDCQEE NAVDVKQYRD KLRTCLDTKL ETVVCTGSVP
     VDKCSLSESG LEPTEETWQS EKLLDSDSHT SKAMRSTGMV VEKKPPDKTV SASFSCETAH
     TKVTFLIGDS MSPDSDTELR SQAVVDQITR HHTKPLKEER GAIDQHQETK QTTKDQSGES
     DIQNMASEEP CELPCWNHSD PESMSLFDEY FNDDSIETRT IDDVPIKTST DSKDHCCMLE
     FSKILCTKNN KQNNEFCKCI QAVPQDSCKT CFPQQDQRDT LSILVPHGDK ESSDKKIAVG
     TEWDIPRNES SDSALGDSES EDTGHDMTRQ VSSYYGGEQE DWAEEDEIPF PGSKLIEVSA
     VQPNIANFGR SLLGGYCSSY VPDFVLQGIG NDERFRQCLM SDLSHAVQHP VLDEPIAEAV
     CIIADMDKWT VQVASSQRRV TDNKLGKEVL VSSLVSNLLH STLQLYKHNL SPNFCVMHLE
     DRLQELYFKS KMLSEYLRGQ MRVHVKELGV VLGIESSDLP LLAAVASTHS PYVAQILL
//