ID   A0A2K5CDU5_AOTNA        Unreviewed;       447 AA.
AC   A0A2K5CDU5;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Growth factor receptor bound protein 7 {ECO:0000313|Ensembl:ENSANAP00000006779.1};
GN   Name=GRB7 {ECO:0000313|Ensembl:ENSANAP00000006779.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000006779.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000006779.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K5CDU5; -.
DR   Ensembl; ENSANAT00000024549.1; ENSANAP00000006779.1; ENSANAG00000021434.1.
DR   GeneTree; ENSGT00940000158710; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01259; PH_APBB1IP; 1.
DR   CDD; cd16140; RA_GRB7; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR015042; BPS-dom.
DR   InterPro; IPR039664; GRB/APBB1IP.
DR   InterPro; IPR046986; GRB7_RA.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR039665; PH_APBB1IP.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR11243; GROWTH FACTOR RECEPTOR-BOUND PROTEIN; 1.
DR   PANTHER; PTHR11243:SF25; GROWTH FACTOR RECEPTOR-BOUND PROTEIN 7; 1.
DR   Pfam; PF08947; BPS; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00788; RA; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00314; RA; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50200; RA; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT   DOMAIN          100..186
FT                   /note="Ras-associating"
FT                   /evidence="ECO:0000259|PROSITE:PS50200"
FT   DOMAIN          229..338
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          1..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..33
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   447 AA;  49389 MW;  1B8E3CB0EB063D41 CRC64;
     MELDLSPPHL GSSPEDLCPA PGTPPGSPRP PEAPVPEEVK RSQPLFIPTT GRKLREEERR
     ATSLPSIPNP FPELCSPPQQ SPILGGPSSV RGLLPRDASC PHVVKVYSED GACRSVEVAA
     GATARHVCEM LVQRTHALSD ETWGLVECHP HLALERGLED HESVVEVQAA WPVGGDSRFV
     FRKNFAKYEL FTSSPHSLFP EKMVSSCLDA HTGVSHEDLI QNFLNVGSFP EIQGFLQLRG
     SGRKLWKRFF CFLRRSGLYY STKGTSKDPR HLQYVADVNE SNVYVVTQGR KLYGMPTDFG
     FCVKPNKLRN GHKGLRIFCS EDEQSRTCWL AAFRLFKYGA QLYKNYQQAQ SRHLRPSCLG
     SPPLRSVSDN TLVAMDFSGH AGRVIENPRE ALSVALEEAQ AWRKKTNHRL SLPMPASGAS
     LSAACSWSGR VSGTPRALSS PCATCRK
//