ID A0A2K5CDY5_AOTNA Unreviewed; 288 AA.
AC A0A2K5CDY5;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=CD200 receptor 1 {ECO:0000313|Ensembl:ENSANAP00000006886.1};
GN Name=CD200R1 {ECO:0000313|Ensembl:ENSANAP00000006886.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000006886.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000006886.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CD200R family.
CC {ECO:0000256|ARBA:ARBA00008215}.
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DR RefSeq; XP_012319445.1; XM_012464022.1.
DR AlphaFoldDB; A0A2K5CDY5; -.
DR Ensembl; ENSANAT00000024657.1; ENSANAP00000006886.1; ENSANAG00000021498.1.
DR GeneID; 105725072; -.
DR GeneTree; ENSGT00390000014496; -.
DR OrthoDB; 5358420at2759; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR GO; GO:0150077; P:regulation of neuroinflammatory response; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR040012; CD200R.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR21462:SF3; CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 2; 1.
DR PANTHER; PTHR21462; CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07686; V-set; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..288
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014350846"
FT TRANSMEM 248..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 137..228
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 288 AA; 32020 MW; 034CAE947E3BE93F CRC64;
MHTWGKMAAS MLLISIIIMV SASDNNSCLM TQVEMQSQRI FLNEVNTSCP VLMGKNAVLC
CPPIALKYLI IITWEIILRG QPSCKKGYRK ETNETKETNC TDERITWVSR PDQNPALQIR
PVAITHDGYY RCIIGTPDGN FHRGYHLQVL VTPEVTLFQS RNGAVVCKAV AGKPAAQISW
IPEGDCVTEQ EYWGNGTVTV KSTCHWEGHD VYTVTCHVSH LTGNKCLSTK LNSGLRTSGS
PALSSLRIIL YVKLSLFVVI LVITGFVFFQ RINDVRMKVE GAGNQLNI
//
