ID   A0A2K5CH16_AOTNA        Unreviewed;       459 AA.
AC   A0A2K5CH16;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Transmembrane protein 145 {ECO:0000313|Ensembl:ENSANAP00000008077.1};
GN   Name=TMEM145 {ECO:0000313|Ensembl:ENSANAP00000008077.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000008077.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000008077.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A2K5CH16; -.
DR   Ensembl; ENSANAT00000025856.1; ENSANAP00000008077.1; ENSANAG00000022076.1.
DR   GeneTree; ENSGT00940000153981; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:InterPro.
DR   InterPro; IPR047831; GPR180/TMEM145.
DR   InterPro; IPR019336; GPR180/TMEM145_TM.
DR   PANTHER; PTHR23252; INTIMAL THICKNESS RECEPTOR-RELATED; 1.
DR   PANTHER; PTHR23252:SF24; TRANSMEMBRANE PROTEIN 145; 1.
DR   Pfam; PF10192; GpcrRhopsn4; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..459
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014330751"
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        239..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        273..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        312..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        349..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        379..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        421..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          176..429
FT                   /note="GPR180/TMEM145 transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF10192"
SQ   SEQUENCE   459 AA;  52281 MW;  A84CA48DCC75E797 CRC64;
     MEPPRAPALR RLLPPLLLLL LSLPSRARAK YVRGNLSSKE DWVFLTRFCF LSDYGRLDFR
     FRYPELPAPN ISGLQAKCCQ NILLYFDDPS QWPAVDPAGE QPGHQPHHTV CLVRLSGEGP
     VEDLGASRTH FSFLACPQVV SEEGTRYLSC SSGRSFRSVR ERWWYIALSK CGGDGLQLEY
     EMVLTNGKSF WTRHFSADEF GILETDVTFL LIFILIFFLS CYFGYLLKGR QLLHTTYKMF
     MAAAGVEVLS LLFFCIYWGQ YATDGIGNES VKILAKLLFS SSFLIFLLML ILLGKGFTVT
     RGRISHAGSV KLSVYMTLYT LTHVVLLIYE AEFFDPGQVL YTYESPAGYG LIGLQVAAYV
     WFCYAVLISL RHFPEKQPFY VPFFAAYTLW FFAVPVMALI ANFGIPKWAR EKIVNGIQLG
     IHLYAHGVFL ILPFPFCIPT KQLGWHRVKL LGLWEAQHH
//