ID A0A2K5CJQ1_AOTNA Unreviewed; 374 AA.
AC A0A2K5CJQ1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Endophilin-B2 {ECO:0000256|ARBA:ARBA00040331};
DE AltName: Full=SH3 domain-containing GRB2-like protein B2 {ECO:0000256|ARBA:ARBA00042180};
GN Name=SH3GLB2 {ECO:0000313|Ensembl:ENSANAP00000008967.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000008967.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000008967.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: Homodimer, and heterodimer with SH3GLB1.
CC {ECO:0000256|ARBA:ARBA00038771}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the endophilin family.
CC {ECO:0000256|ARBA:ARBA00006697}.
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DR AlphaFoldDB; A0A2K5CJQ1; -.
DR Ensembl; ENSANAT00000026753.1; ENSANAP00000008967.1; ENSANAG00000022410.1.
DR GeneTree; ENSGT00940000155841; -.
DR OMA; QMSFYAQ; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd07617; BAR_Endophilin_B2; 1.
DR CDD; cd11944; SH3_Endophilin_B2; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR035640; Endophilin_B2_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14167:SF68; ENDOPHILIN-B2; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 24..266
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 314..374
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT COILED 179..213
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 374 AA; 41682 MW; 0723E9E5BB7D245A CRC64;
MDFNMKKLAS DAGIFFTRAV QFTEEKFGQA EKTELDAHFE NLLARADSTK NWTEKILRQT
EVLLQPNPSA RVEEFLYEKL DRKVPSRVTN GELLAQYMAE AASELGPTTP YGKTLLKVAE
AEKQLGAAER DFIHTASISF LTPLRNFLEG DWKTISKERR LLQNRRLDLD ACKARLKKAK
AAEAKATLWN DEVDKAEQEL RVAQTEFDRQ AEVTRLLLEG ISSTHVNHLR CLHEFVKSQT
TYYAQCYRHM LDLQKQLGRF PGTFVGTTEP ASPPLSSTSP TTAAATMPVV PSVASLAPPG
EASLCLEEVA PPASGTRKAR VLYDYEAADS SELALLADEL ITVYSLPGMD PDWLIGERGN
KKGKVPVTYL ELLS
//
