ID A0A2K5CL76_AOTNA Unreviewed; 138 AA.
AC A0A2K5CL76;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Cytochrome c oxidase subunit 4 {ECO:0000256|RuleBase:RU367145};
GN Name=COX4I1 {ECO:0000313|Ensembl:ENSANAP00000009460.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000009460.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000009460.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Component of the cytochrome c oxidase, the last enzyme in the
CC mitochondrial electron transport chain which drives oxidative
CC phosphorylation. {ECO:0000256|RuleBase:RU367145}.
CC -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC {ECO:0000256|ARBA:ARBA00004673, ECO:0000256|RuleBase:RU367145}.
CC -!- SUBUNIT: Component of the cytochrome c oxidase (complex IV, CIV), a
CC multisubunit enzyme composed of 14 subunits.
CC {ECO:0000256|RuleBase:RU367145}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004434,
CC ECO:0000256|RuleBase:RU367145}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004434, ECO:0000256|RuleBase:RU367145}.
CC -!- SIMILARITY: Belongs to the cytochrome c oxidase IV family.
CC {ECO:0000256|ARBA:ARBA00008135, ECO:0000256|RuleBase:RU367145}.
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DR AlphaFoldDB; A0A2K5CL76; -.
DR Ensembl; ENSANAT00000027253.1; ENSANAP00000009460.1; ENSANAG00000022720.1.
DR GeneTree; ENSGT00390000002407; -.
DR UniPathway; UPA00705; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0005751; C:mitochondrial respiratory chain complex IV; IEA:InterPro.
DR GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IEA:InterPro.
DR CDD; cd00922; Cyt_c_Oxidase_IV; 1.
DR Gene3D; 1.10.442.10; Cytochrome c oxidase subunit IV; 1.
DR InterPro; IPR013288; Cyt_c_oxidase_su4.
DR InterPro; IPR004203; Cyt_c_oxidase_su4_fam.
DR InterPro; IPR036639; Cyt_c_oxidase_su4_sf.
DR PANTHER; PTHR10707:SF12; CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR10707; CYTOCHROME C OXIDASE SUBUNIT IV; 1.
DR Pfam; PF02936; COX4; 1.
DR PRINTS; PR01873; CYTCOXIDASE4.
DR SUPFAM; SSF81406; Mitochondrial cytochrome c oxidase subunit IV; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Membrane {ECO:0000256|RuleBase:RU367145};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW ECO:0000256|RuleBase:RU367145};
KW Mitochondrion inner membrane {ECO:0000256|RuleBase:RU367145};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Transmembrane {ECO:0000256|RuleBase:RU367145};
KW Transmembrane helix {ECO:0000256|RuleBase:RU367145}.
FT TRANSMEM 102..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367145"
SQ SEQUENCE 138 AA; 15636 MW; 7671F9B18E9DB219 CRC64;
MLATRVFSLV GKRAISTSVC VRAHGSVVKS EDYALPSYVD RRDYPLPDVA HVRHLSASQK
ALKEKEKASW SSLSMDEKVE LYRIQFKESF AEMNRGSNEW KTVVGAAMFF IGFTAILIIL
EKRYVDHGCS LDLVVHRL
//
