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Database: UniProt
Entry: A0A2K5CRY4_AOTNA
LinkDB: A0A2K5CRY4_AOTNA
Original site: A0A2K5CRY4_AOTNA 
ID   A0A2K5CRY4_AOTNA        Unreviewed;      3116 AA.
AC   A0A2K5CRY4;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   10-FEB-2021, entry version 17.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSANAP00000011462};
GN   Name=CENPF {ECO:0000313|Ensembl:ENSANAP00000011462};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000011462, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000011462}
RP   NUCLEOTIDE SEQUENCE.
RA   Hughes D.S., Murali S., Raveendran M., Korchina V., Bandaranaike D.,
RA   Bellair M., Blankenburg K., Chao H., Dahdouli M., Dinh H., Doddapaneni H.,
RA   Jayaseelan J., Khan Z., Kovar C., Kurapati P., Le B., Lee S.,
RA   Lorensuhewa L., Mathew T., Narasimhan A., Okwuonu G., Osuji N., Otenyo P.,
RA   Qu C., Quiroz J., Raj R., Rajbhandari K., Santibanez J., Skinner E.,
RA   Wang Y., Xin Y., Han Y., Muzny D.M., Richards S., Worley K.C., Rogers J.,
RA   Gibbs R.A.;
RT   "Owl monkey reference genome and diversity panel.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSANAP00000011462}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2018) to UniProtKB.
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DR   RefSeq; XP_012315068.1; XM_012459645.1.
DR   Ensembl; ENSANAT00000029272; ENSANAP00000011462; ENSANAG00000023683.
DR   GeneID; 105722256; -.
DR   CTD; 1063; -.
DR   GeneTree; ENSGT00730000111187; -.
DR   OMA; YNAQLVQ; -.
DR   OrthoDB; 205405at2759; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR   GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR   GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR   GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR   GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR   GO; GO:0030496; C:midbody; IEA:Ensembl.
DR   GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR   GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0045120; C:pronucleus; IEA:Ensembl.
DR   GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR   GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT   DOMAIN          1..307
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          2133..2272
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2315..2454
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2971..3015
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          193..235
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1662..1694
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1721..1742
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2902..2959
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          3027..3116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          164..191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          280..384
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          418..459
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          477..497
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          523..615
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          623..650
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          658..720
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          725..752
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          832..873
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          903..989
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1029..1056
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1082..1159
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1196..1244
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1286..1313
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1549..1612
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1624..1646
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1792..1861
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1913..1947
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1972..1999
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2004..2045
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2049..2080
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2109..2136
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2144..2280
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2298..2318
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2326..2469
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2477..2546
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2564..2605
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2620..2686
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2691..2711
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2713..2740
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2755..2775
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2783..2827
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2838..2865
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2873..2893
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1671..1694
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2918..2957
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3031..3082
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3116 AA;  358096 MW;  CF5E708C1B3CF4B6 CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKEKQQRQFQ LDSLEAALQK QKQKVENEKT
     EGTNLKRENQ RLIEICESLE KTKQKISHEL QVKESQVNFQ EGQLNSGKKQ IEKLEQELKR
     CKSELERSQQ AAQSADVSLN PCNTPQKIFT TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
     LEAEVKALQA KKANQTLPQT SMNHRDIARH QASSSVFSWQ QDKTPSRLSS SSQKTPIRRD
     FSASYFSGEQ EVTPSRSTLQ IGKRDANSSF FDNSNSPHLL DQLKVQNQEL RSKINELELH
     LQGQEKEMKS QVNKFQELQL QLEKAKVELS EKEKVLNKCR DELVRTTAQY DQASTKCTAL
     EQKLKKLTED LSCQRQNAES ARCSLEQRIK EKEKEFQEEL SCQQRSFQTL DQESIQMKAK
     LTQELQQAKN MHNVLQAELD KVTSIKQQLE KNVEEFKQKL CRSEQAFQAS EIKENELRRS
     TEEMKKENSL LKSQSEQTAR EVCHLEAELK KVKQCLNQSQ NFAEEMKVKN TSQETMLKDL
     QEKINQQENS LTLEKLKLAV ADLEKQRDCS QDLLKKREHH IEQLNDKLNK IEKESKALLS
     ALELKNKEYE ELKEEKTLFS CWKSENEKLL TQMESEKESL QSKINHLETC LKTQQIKSHE
     YNERVRTLEM DRENLSVEIR NLHNVIDSKS VEVETQKQAY EELQQKAEFS DQKHQKEIEN
     MCLKTFQLTG QVEDLERKLQ LLSNEIMNKD RCYQDLHAEY ESLRDLLKSK DASLVTNEDH
     QRSLLAFDQQ LAMHNSFANI IGEQRSMPSE RSECHLEADQ SPKNSAILQN RVDSLEFSLE
     SQKQMNSDLQ KQCEELVQIK GEIEENLMRA EQMHQSFVAE TSQRISKLQE DTSAHQNVVA
     ETLSALENKE KELQLLNFKL EMEQAEIQEL KKSNHLLEDS LKELQLLSET LSMEKKEMSS
     IISLNKREIE ELTQENGSLK EINASLNQEK MNLIQKSESF ANCINEREKS ISELSDQYKQ
     EKLILLQRCE ETGNAYEDLS QKYKAAQEKN FKLESLLNEC TTLCEHRKND LEQLKEAFAK
     EHQEFLTKLA FAEERNQNLI LELETVQQDL RSEMTDIQNN SKSEADGLKQ EIMTLKEEQN
     KMQKEVNDLL QENEQLMKLM KTEHECQNLA LESIRNSRKE RESERNQCNF KLQMNLEVKE
     ISLDSYNAQL VQLEAMLRNM ELKLKESERE KECLQNELQT IRGKLETRNL QDMQSQEISG
     LKDCEIDADE KYISVLRELS TTQNDNGHLQ CSLQTAMNKL NELEKMCEKL QTDKCELVSE
     LNESRSGCIT ATRKMAEEVG KLVNEVKILN DDSGLLHGEL MEGMPGGEFG EQPNEQHPMS
     LAPLDDSNSY EHLALSNKEV QMHFAELQDK FSSLQSEHKI LHDQHCQMSS KMLELQTYVD
     SLKAENLVLS TNLRNFQGDL VKEMQPGLEE GLVPSLSSSC LPVSPSLSSL GDCSFYKALL
     EQTGEMSLLN NLEGNVSANQ SSVDEVFCNS LEEENLTKKE IPSAPAKSVE ELESLCQVYQ
     QSLEKLEEKM ESQEIMKNKE IQELEQLLSS ERQELDCLRK QYLSENEQWQ QKLTSVTLEM
     ESKLAAEKKQ TEQLSLELEV ARLQLQGLDL SSRSLLGIDT EDAIQGQNES GDIKESKEHT
     SETTEGRPKH DAHHICDKDV QQDLSLNIEK ITETGAVKLT GECSGEQSPD TSYETPGEDK
     TRGYSECISE LSFSGPNALV PMDFLGNQEN IQNLQLQVKE TSNENLRLLH VIEDRDRKVE
     SLLNEMNELD SKLHLQEVQL MTKIEACIEL EKTVEELKKE NSDLSEKLES FSCDNQELLQ
     RVETSEGLSS NLEMCANKSS HEDIEDNVAK VNNSWKERFL DVENELSRIR SEKASIEHQA
     LSLEAALERV QTEKLCLEKD NENKQKVIVC LEEDLSVVTS ERNQLRGELD TMSKKTLELD
     QLSEKMKEKT QELESHQSKC LHCLQVAEAE VKEKTELLQT LSSDMSEVLK EKTHIQEKLQ
     SLEKDSQALS LAKCELENQI AQLKKEKELL VKESESLQAR LSESDYEKLN VSKALEAALV
     EKGEFALRLS STQEEVHQLR RGIEKLRVRI EADEKKQLHV AEKLKERERE NDSLKDKVEN
     LERELQMSEE NQELVILDAE NSKAEVETLK TQLEEMARSL KVFELDHVML RSEKENLTKQ
     LQEKQGQVSE LDKLLSSFKS LLEEKEQAEI QIKEESKTAV EMLQNQLKEL NDAVAALYGD
     QETVKATEQS LDPPVEEVHQ LRNSIEKLRV HLEADEKKQL CVLEQLKEGE HLADLLKGRV
     ENLERELELS RKNQEHAVLE AENSKGEVET LKAKIEGMTQ SLRDLELDLV TIRSEKENLT
     NALQKEQERI SELEIINLSF ENILQEKEQE KVQIKEKSNT AVEILQTQLK ELNERVAALR
     NDQETCKAKE QNLSSQVDCL ELEKAQLLQG LEEAKNNYIV LQSSVNGLIQ EVEDGKQKLE
     KKDEEISRLK NQIQDQEQLV SKLSEVEGEQ QLLKKQNLEL VNLTVELKQK IQVLQSKNAS
     LQDTLEVLQS SYKNLENELE LTKMDKMSFV EKVNTMTTKE TELQREMHEM AQETAELQEE
     LSAEKNRLTG ELQLLLEEIK SSKDQLKELT LENSELKKSL DCMHEDQVEK EGKVREEIAD
     YQLRLHEAEK KHQAVLLDTN KQYEIEIQKY QEKLSSKEEC LSSQKLEMDL LKCSKEELSN
     SLKATTQVLE ELKKTKMDNL KYVNQLKKEN ERAQGKIKLL MKSCKQLEEE KEMLQKVLSQ
     HEAAQERQKT GTVLDAKVDE FMTEIKELKE TLEEKTKEAD EYLDKYCSLL ISHEKLEKAK
     EMLETQVAHL CSQQSKQDFR GSPLLDAAVP GPSPIPSATE KRLSSGQNKA SGKRQRSSGI
     WENGRGPTPS TPETFSKKSK KAVMKGIHPA EDTEDTEFEP EGLPEVVKKG FADIPTGKTS
     PYILRRTTMA TRTSPRLAAQ KLALSPLSLG KENLAESSKP TAGGSRSQKV KVAQQSPVDS
     GTVLREPTTK SLLVNNLQER SPADSPREGL RAKRGRLTPS PKAGVEPKGS ENFAWA
//
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