ID   A0A2K5CS03_AOTNA        Unreviewed;       491 AA.
AC   A0A2K5CS03;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=Double-stranded RNA-binding protein Staufen homolog 2 {ECO:0000256|ARBA:ARBA00024122};
GN   Name=STAU2 {ECO:0000313|Ensembl:ENSANAP00000011481.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000011481.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000011481.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A2K5CS03; -.
DR   Ensembl; ENSANAT00000029292.1; ENSANAP00000011481.1; ENSANAG00000023588.1.
DR   GeneTree; ENSGT00940000154977; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd19882; DSRM_STAU2_rpt2; 1.
DR   CDD; cd19884; DSRM_STAU2_rpt3; 1.
DR   CDD; cd19886; DSRM_STAU2_rpt4; 1.
DR   Gene3D; 3.30.160.20; -; 4.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR044464; STAU2_DSRM_2.
DR   InterPro; IPR044473; STAU2_DSRM_3.
DR   InterPro; IPR044474; STAU2_DSRM_4.
DR   InterPro; IPR032478; Staufen_C.
DR   PANTHER; PTHR46054:SF1; DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 2; 1.
DR   PANTHER; PTHR46054; MATERNAL EFFECT PROTEIN STAUFEN; 1.
DR   Pfam; PF00035; dsrm; 3.
DR   Pfam; PF16482; Staufen_C; 1.
DR   SMART; SM00358; DSRM; 3.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 4.
DR   PROSITE; PS50137; DS_RBD; 3.
PE   4: Predicted;
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00266}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          75..161
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          187..254
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   DOMAIN          287..355
FT                   /note="DRBM"
FT                   /evidence="ECO:0000259|PROSITE:PS50137"
FT   REGION          31..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          158..183
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          368..391
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   491 AA;  53994 MW;  885D0F553D2604C3 CRC64;
     MVARPLHSRE GQPESLGKMF SVQLSLGEQT WESEGSSIKK AQQAVANKAL TESTLPKPVQ
     KPPKSNVNNN PGSITPTVEL NGLAMKRGEP AIYRPLDPKP FPNYRANYNF RGMYNQRYHC
     PMPKIFYVQL TVGNNEFFGE GKTRQAARHN AAMKALQALQ NEPIPEKSPQ NGESGKDMDD
     DKDANKSEIS LVFEIALKRN MPVSFEVIKE SGPPHMKSFV TRVSVGEFSA EGEGNSKKLS
     KKRAATTVLQ ELKKLPPLPV VEKPKLFFKK RPKTIVKAGP EYGQGMNPIS RLAQIQQAKK
     EKEPDYVLLS ERGMPRRREF VMQVKVGNEV ATGTGPNKKI AKKNAAEAML LQLGYKASTN
     LQDQLEKTGE NKGWSGPKAG FPEPTNNTPK GILHLSPDVY QEMEASRHKV ISGTTLGYLS
     PKDMNQPSSS FFSISPTSNS SATIARELLM NGTSSTAEAI GLKGSSPTPP CSPVQPSKQL
     EYLARIQGFQ V
//