ID A0A2K5CW73_AOTNA Unreviewed; 2069 AA.
AC A0A2K5CW73;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Multiple PDZ domain crumbs cell polarity complex component {ECO:0000313|Ensembl:ENSANAP00000012941.1};
GN Name=MPDZ {ECO:0000313|Ensembl:ENSANAP00000012941.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000012941.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000012941.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR Ensembl; ENSANAT00000030763.1; ENSANAP00000012941.1; ENSANAG00000024262.1.
DR GeneTree; ENSGT00940000155586; -.
DR Proteomes; UP000233020; Unplaced.
DR CDD; cd00992; PDZ_signaling; 13.
DR Gene3D; 2.30.42.10; -; 13.
DR Gene3D; 1.10.287.650; L27 domain; 1.
DR InterPro; IPR015132; L27_2.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR036892; L27_dom_sf.
DR InterPro; IPR032078; MPDZ_u10.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR19964; MULTIPLE PDZ DOMAIN PROTEIN; 1.
DR PANTHER; PTHR19964:SF44; PATJ HOMOLOG; 1.
DR Pfam; PF09045; L27_2; 1.
DR Pfam; PF16667; MPDZ_u10; 1.
DR Pfam; PF00595; PDZ; 13.
DR SMART; SM00228; PDZ; 13.
DR SUPFAM; SSF101288; L27 domain; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 13.
DR PROSITE; PS51022; L27; 1.
DR PROSITE; PS50106; PDZ; 13.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT DOMAIN 1..62
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 136..223
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 256..336
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 376..462
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 552..633
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 699..775
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1007..1075
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1150..1238
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1349..1432
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1482..1563
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1628..1711
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1724..1806
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1861..1947
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1986..2069
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 346..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1277..1321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1568..1612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1577..1612
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2069 AA; 221491 MW; 83A124756B017B93 CRC64;
LEAIDKNRAL QAAERLQTKL RERGDVANED KLSLLKSVLQ SPLFSQILSL QTSVQQLKDQ
VNIATSATSN TEYAHIPHLS PAVIPTLQNE PFLLSPNNGN LEALTGSGIL HINGKPACDE
FDQLIKNMAQ GRHVEVFELL KPPSGGLGFS VVGLRSENRG ELGIFVQEIQ EGSVAHRDGR
LKETDQILAI NGQALDQTIT HQQAISILQK AKDTVQLVIA RGSLPQLISP IVSRSPSAAS
TISAHSNPVH WQHVETIELV NDGSGLGFGI IGGKATGVIV KTILPGGVAD QHGRLCSGDH
ILKIGDTDLT GMSSEQVAQV LRQCGNRVKL MIARGAIEEH TAPTSLGITL SSSPSSTPES
RVDASTQKGE ESETFDVELT KNVQGLGITI AGYIGDKRLE PSGIFVKSIT KSSAVEHDGR
IQIGDQIIAV DGTNLQGFTN QQAVEVLRHT GQTVVLTLMR RGVKQEAELM SREDITKDAD
LSPVNASLSK ENYEKDEDSL SLRRNTSILP IEEEGYPLLS AEIEEIEDAQ QQEAALLAKW
QRIMGINYEI VVAHVSKFSE NSGLGISLEA TVGHHFIRSV LPEGPVGHSG KLFSGDELLE
VNGITLRGEN HQDVVNILKE LPIEVTMVCC RRTVPPTTQS ELDSLDLCDI ELTEKPHVDL
GEFIGSSETE DPVLSMTDAG QSTEEVQAPL AMWEAGIQHI ELEKGSKGLG FSILDYQDPI
DPASTVIVIR SLVPGGIAEK DGRLLPGDRL MFVNDVNLEN SSLEEAVEAL KGAPSGTVRI
GVAKPLPLSP EEGYVSAKED SFLYPPHSCE EEGLADKPLF RADLALVDAN DVDLVDESTF
ESQYSPDNDS IYSTQASVLS LHGSSCGDGL NYGSSLPSSP PKDVIENSSN PVLDLHMSLE
ELYTQNLLQR QDENTPSVDI SMGTTSGFTI NDCTPANAIE QQCECENTIV WNESHLPSEV
ISSAELPSVL LDSAGKSSEY LLEQSSLSSN AECVMLQNVS KESFERTITI AKGNSSLGMT
VSANKDGLGM IVRSIIHGGA ISRDGRIAIG DCILSINEES TISVTNAQAR AMLRRHSLIG
PDIKITYVPA EHLEEFKISL GQQSGRMMTL DVFSSYAGRD IPELPEREEG EGEESELQNT
AYSNWNQPRR VELWREPSKS LGISIVGGRG MGSRLSNGEV MRGIFIKHVL EDSPAGKNGT
LKPGDRVVEV DGMDLRDASH EQAVEAIRKA GNPVVFMVQS IINRPRKSPL PSLPHSLYPK
YNFSSTNPFA DSLQINADKA PSQSESEPEK APLCNVSPPP PSAFAEMSSD HAHSSASKIS
QDVDKEDEFG YSWKNIRERY GTLIGELHMI ELEKGHSGLG LSLAGNKDRS RMSVFIVGID
PNGAAGKDGR LQVADELLEI NGQILYGRSH QNASSIIKCA PSKVKIIFIR NKDAVNQMAV
CPGNAVEPLP STSENLQNKE TEPTVTTSDG VVDLSSFKNV QHLELSKDQG GLGIAISEED
TLSGVLIKSL TEHGVAATDG RLKIGDQILA VDDEIVVGYP VEKFISLLKT AKKTVKLTIR
AENADSQAVP SAAGAASGEK KNSSQSLIIP QSGSPEPESI RNTSRSSTPA IFASDPATCP
IIPGCETTIE ISKGRTGLGL SIVGGSDTLL GAIIIHEVYE EGAACKDGRL WAGDQILEVN
GIDLRKATHD EAINVLRQTP QRVRLTLYRD ETSYKEEEVC DTLTIELQKK PGKGLGLSIV
GKRNDTGVFV SDIVKGGIAD ADGRLMQGDQ ILMVNGEDVR NATQEVVAAL LKCSLGTVTL
EVGRIKAGAF HSERRPSQSS QVSEGSLSSF TFPLSGSSTS ESLESSSKKN ALASEIQGLR
TVEIKKGPTD SLGISIAGGV GSPLGDVPIF IAMMHPTGVA AQTQKLRVGD RIVTICGTST
EGMTHTQAVN LLKNAPGSIE MQVVAGGDVS VVTGHQQEPA SSSLSFTGLT SSSIFQDDLG
PPQCKSITLE RGPDGLGFSI VGGYGSPHGD LPIYVKTVFA KGAASEDGRL KRGDQIIAVN
GQSLEGVTHE EAVAILKRTK GTVTLMVLS
//
