ID   A0A2K5CWU8_AOTNA        Unreviewed;       463 AA.
AC   A0A2K5CWU8;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=DNA polymerase II subunit 2 {ECO:0000256|ARBA:ARBA00032930};
GN   Name=POLE2 {ECO:0000313|Ensembl:ENSANAP00000013175.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000013175.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000013175.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase epsilon subunit B family.
CC       {ECO:0000256|ARBA:ARBA00009560}.
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DR   AlphaFoldDB; A0A2K5CWU8; -.
DR   Ensembl; ENSANAT00000030997.1; ENSANAP00000013175.1; ENSANAG00000024494.1.
DR   GeneTree; ENSGT00390000012435; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0008622; C:epsilon DNA polymerase complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.60.21.60; -; 1.
DR   InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR   InterPro; IPR024639; DNA_pol_e_bsu_N.
DR   InterPro; IPR016266; POLE2.
DR   PANTHER; PTHR12708:SF0; DNA POLYMERASE EPSILON SUBUNIT 2; 1.
DR   PANTHER; PTHR12708; DNA POLYMERASE EPSILON SUBUNIT B; 1.
DR   Pfam; PF04042; DNA_pol_E_B; 1.
DR   Pfam; PF12213; Dpoe2NT; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT   DOMAIN          2..36
FT                   /note="DNA polymerase epsilon subunit B N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12213"
FT   DOMAIN          223..424
FT                   /note="DNA polymerase alpha/delta/epsilon subunit B"
FT                   /evidence="ECO:0000259|Pfam:PF04042"
SQ   SEQUENCE   463 AA;  52141 MW;  34523F6662390A6D CRC64;
     LELEDKLEKI IDAVEKQPLS SNMIERSVVE AAVQECSQSI DETILLMTNH PAPNLFGTAR
     DKAELFRERY TILHQRTHRH ELFTPPVIGS NPDESGSKFQ LKTIETLLGS TTKIGDVIVL
     GMITQLKEGK FFLEDPTGTV QLDLSKAQFH SGLYTEACFV LAEGWFEDQV FHVNAFGFPP
     TEPSSTTRAY YGSINFFGGP SNTSVKTSAK LKQLEEENKD AMFVFLSDVW LDQVEVLEKL
     RIMFSGYSPA PPTCFILCGN FSSAPYGKNQ VQALKDSLKT LADIICEYPD IHQSSRFVFV
     PGPEDPGFGS ILPRPPLAES ITNEFRQRVP FSVFTTNPCR IQYCTQEIIV FREDLVNKMC
     RNCVRFPSSN LAIPNHFVKT ILSQGHLTPL PLYVCPVYWA YDYALRVYPL PDLLVIADKY
     DPFTMTNTEC LCINPGSFPR SGFSFKVFYP SSKTVEDSKL QGF
//