ID A0A2K5CYU6_AOTNA Unreviewed; 428 AA.
AC A0A2K5CYU6;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=WD repeat, SAM and U-box domain-containing protein 1 {ECO:0000256|ARBA:ARBA00020894};
GN Name=WDSUB1 {ECO:0000313|Ensembl:ENSANAP00000013869.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000013869.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000013869.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2K5CYU6; -.
DR Ensembl; ENSANAT00000031698.1; ENSANAP00000013869.1; ENSANAG00000024850.1.
DR GeneTree; ENSGT00940000157230; -.
DR OMA; YSEKAHD; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46573; WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR46573:SF1; WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF04564; U-box; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS51698; U_BOX; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 50..91
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 93..134
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 146..167
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 276..310
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 331..395
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 377..428
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
SQ SEQUENCE 428 AA; 47363 MW; 09C109CC254D2B2D CRC64;
MVKLIHTLAD HGDDVNCCAF SFSLLATCSL DKTIRLYSLS DFTELPHSPL KFHTYAVHCC
CFSPSGHILA SCSTDGTTVL WNTENGQTLA VMEQPSGSPV RVCQFSPDST CLASGAADGT
VVLWNVQSYK LYRCGSVKDG SLVACAFSPN GSFFVTGSSC GDLTVWDDKM RCLHSEKAHD
LGITCCNFSS QPVSDGEQGL QFFRLASCGQ DCQVKIWVVS FTHIFGFELK YKSTLSGHCA
PVLACAFSHD GQMLVSGKCK AVFVVFQNTE NILHTLTQHT RYVTTCAFAT HTLLLATGSM
DKTVNIWQFD LETLCQARST EDHLKQFTED WSEKDVSTWL CAQGLKDLVG IFKMNNIDGK
ELLNLTKESL ADDLKIDGYS YEKEAMENWI STKKRTSPMT NLVLSSVVLT PNRTLKMAIN
RWLETHQK
//
