ID   A0A2K5D1E1_AOTNA        Unreviewed;       722 AA.
AC   A0A2K5D1E1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Leucine rich repeats and calponin homology domain containing 3 {ECO:0000313|Ensembl:ENSANAP00000014768.1};
GN   Name=LRCH3 {ECO:0000313|Ensembl:ENSANAP00000014768.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000014768.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000014768.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A2K5D1E1; -.
DR   Ensembl; ENSANAT00000032602.1; ENSANAP00000014768.1; ENSANAG00000025267.1.
DR   GeneTree; ENSGT00940000158330; -.
DR   Proteomes; UP000233020; Unplaced.
DR   CDD; cd21272; CH_LRCH3; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR48051; -; 1.
DR   PANTHER; PTHR48051:SF44; LEUCINE RICH REPEATS AND CALPONIN HOMOLOGY DOMAIN CONTAINING 3; 1.
DR   Pfam; PF00307; CH; 1.
DR   Pfam; PF13855; LRR_8; 2.
DR   SMART; SM00033; CH; 1.
DR   SMART; SM00364; LRR_BAC; 4.
DR   SMART; SM00369; LRR_TYP; 5.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   PROSITE; PS50021; CH; 1.
PE   4: Predicted;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          597..710
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   REGION          483..511
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          527..554
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          567..594
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   722 AA;  80255 MW;  C4757B6A443FD657 CRC64;
     MAAAGSVAVA AAAGYSGTAA SGGNLPGVPC GSGSGAGPGS GPGSWSRSLD RALEEAAVTG
     VLSLSGRKLR EFPRGAGNHD LTDTTRADLS RNRLSEIPIE ACHFVSLENL NLYQNCIRYI
     PEAILNLQAL TFLNISRNQL STLPVHLCNL PLKVLIASNN KLVSLPEEIG HLRHLMELDV
     SCNEIQTIPS QIGNLEALRD LNVRRNHLVH LPEELAELPL IRLDFSCNKI TVIPVCYRNL
     RHLQMITLDN NPLQSPPAQI CIKGKIHIFK YLNIQACKIA PDLPDYDRRP LGFGSCHEEL
     YSSRPYGALD SGFNSVDSGD KRWSGNEPTD EFSDLPLRVA EITKEQRLRR ESQYQENRGS
     LVVTNGGVEH DLDQIDYIDS CTAEEEEDEG SPIKPVAIRE FQKTEDMRRY LHQNRVPVEP
     SSLLSLSPSH NQLSHTDLEL HRRREQLVER TRREAQLAAL QYEEEKIRTK QIQRDAVLDF
     VKQKASQSPQ KQQPLLDDEC PFPSRRSQHT DDSALLVVDD RPNALLSSST TETVHHSPAY
     SFPAATQRSQ SQRPESFLFR ADVRAETNKG HASPLPPSAV PATESIDSVT RQNSRQREEE
     LELIDQLRKH IEYRLKVSLP CDLGAALTDG VVLCHLANHV RPRSVPSIHV PSPAVPKLTM
     AKCRRNVENF LEACRKIGVP QEQLCLPLHI LEEKGLSQVA VTVQALLELA PPKQQQHQLS
     AV
//