ID A0A2K5D7Y0_AOTNA Unreviewed; 1882 AA.
AC A0A2K5D7Y0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Tetratricopeptide repeat domain 6 {ECO:0000313|Ensembl:ENSANAP00000017018.1};
GN Name=TTC6 {ECO:0000313|Ensembl:ENSANAP00000017018.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000017018.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000017018.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 37293.ENSANAP00000017018; -.
DR Ensembl; ENSANAT00000034872.1; ENSANAP00000017018.1; ENSANAG00000026374.1.
DR GeneTree; ENSGT00940000161150; -.
DR Proteomes; UP000233020; Unplaced.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 10.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44858; TETRATRICOPEPTIDE REPEAT PROTEIN 6; 1.
DR PANTHER; PTHR44858:SF1; UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE SPINDLY-RELATED; 1.
DR Pfam; PF00515; TPR_1; 2.
DR Pfam; PF07719; TPR_2; 1.
DR Pfam; PF13181; TPR_8; 3.
DR SMART; SM00028; TPR; 24.
DR SUPFAM; SSF48452; TPR-like; 5.
DR PROSITE; PS50005; TPR; 11.
DR PROSITE; PS50293; TPR_REGION; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 914..947
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 981..1014
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1082..1115
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1220..1253
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1366..1399
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1538..1571
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1572..1605
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1643..1676
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1710..1743
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1744..1777
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1812..1845
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 38..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 232..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 388..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..254
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1882 AA; 215334 MW; 162B554A60C0EBE2 CRC64;
MSTIPKHFGL KYKEESYMFK ELEKVRQETK KDFLRFKQKL ASKPGVGEGP LHNPHAPSPA
RRTRLSRAGV RTSRGSSPAK GPARSAAALL QEVLGGAPRP SGLGEAAAPG KTRPFLPRDF
NLRSSAFLRH LPQKKPPVIA SGFGTARPVV LLPPPEPPAK RRDLESPRLA GPRRVLDLAR
GREESQAVAP LAGPCKARER KVSSVSAGDG SAEAGGGRRK VRIRTCFGSE SLAREAPEAA
GSRTRGERES WPPCDTREAA GQALLPARVV PTSIEEIIAS LQSEAQLASD QTIKELIRSV
LGQNYDIKME DISLMGKMYL KTSSIQAETP QIQAEHSFQM GAEESQMSMR KELPEAISSI
FQIEQEGIER GPLEVESTIF KPQETLQVQP AEELSKPLEH GQPTSDSKEA KPMPLKAKSS
EFLQIKGKQI KQMRKCKSLR PRKSSKPLCD KKLQRKIPRD YSMPHLHKLC TTIPARQLPV
DLCLASRVYH TANRKGHNAL LGIFGTSFLD DRFTDEEQTE RILYGIPVMD DNQEHVHVPP
TPRGIPPELA QGTREHVHKP HLQVLGEEMC AYPEFTKLFW NTAAPKFSVP ESVMKETLYP
KYESVQASRL LTEKFSPDIS VLTLHQYSRT NFSCFLLRKS ASLESVQKCF SAQPTQLRRA
KSSVDLRKEE IIAPLEIKND MQSSIKEVLF QKANELKRQL QLLKQNKTED PIPVKENVDH
IFENICEKHS LRNLSLSLVE ASKKAGMNDI VYPKKKKTKW KKRLKQRKLT FVYEELAKPP
KSLERSESHG ILPEQKKYLF KVPLYERQIR CPSLPLYLNF EKFVQMKGGI PENSDPRTWA
LDMLVEHKYQ RTPIKEEVDK ISVLKDSPEI VKEPPKLKLN DNVESNLPPE VIKHYESEVK
ILTEEINNKT EYPAFAYCRR GAIYRKLGKL QSAMNDLQKA MLLEPFFLNA YWHRHLIYLF
QDKINEALDD LNIHKYNKNN TEAYLSKAEI YRGKKDITLA ILNYTQAIKC RPTDADIYFR
RGEMHEIANK VLAIDDFSKC IFYDPKRTDA LLKRGLFYYE NENWFAAIQD FTALLNIDHQ
NSQARTYRGM AYVKRKFYKQ ATQDFSAAVH LDPNNWLALY YRGCLFRKSN PFRALQDYSV
SALINDGYEN LSCFLHRGIV YAHLKLWLLA ICDFETVISL ERTITLAYIN IGLIQLLHLD
NYTEAIWQFS EAIRIDPLCI QSYICRAETY FKLHKLKKAV NELSRAIHLQ PDGIQLYIRR
GQYLLMMRCY NLAKFTIYQV AEMDKGLNEL SPIQQALIYS FCENHDKAIE VLDGISWNRT
DMTMYALLAK VQMKAKRTKE AVRTLKKALD VISHSDKGPN ATAISADCLY NLGLCYMEEG
NLQMAFDSFT KAVKANPDFA ESFYQRGLCK AKLHKDSSIL DFNCAITLNP KHYQAYLSRV
AFYGLKGRYS KAILNCNMAM KIYPDSVRAY LYRGVLKYYN KTYKLAITDL TIAINMDKNS
YIAFYNRALC YTKIRELQMA LTDYGIVLLL DATETVKLNT FLNRGLIYIE LGQYGFALED
FKQAELISQT NGSLYHATAM CHHRINEFEE AINFFTWALK INPCFLDAYV GRGNSYMEYG
LDEATKKAQK DFLKALHINP GYIKARISLG YNLQIQGKFQ KAWNHFTIAM DIDPKNYLAY
EGRAVVCLQM GNNFAAMQDI NAAMKINTTA EFLTNRGVIH EFMGHKQNAM KDYQEAISLN
PKYSLAYFNA GNIYFHHRQF SQASDYFSKA LKFDPENEYV LMNRAIANTI LKNYEEAKED
FANLIERCPF WAAVYFNRAH FYYCLKQYEL AEEDLNKALS LKPNDALVYN FRAKVRGKIG
LSEEAMADYN QALDLEDYAS FT
//
