ID A0A2K5DEU0_AOTNA Unreviewed; 541 AA.
AC A0A2K5DEU0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Platelet-derived growth factor receptor-like protein {ECO:0000256|ARBA:ARBA00019671};
GN Name=FLT1 {ECO:0000313|Ensembl:ENSANAP00000019479.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000019479.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000019479.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: Forms a complex composed of PDGFRL, TNK2 and GRB2.
CC {ECO:0000256|ARBA:ARBA00011360}.
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DR AlphaFoldDB; A0A2K5DEU0; -.
DR Ensembl; ENSANAT00000037351.1; ENSANAP00000019479.1; ENSANAG00000027521.1.
DR GeneTree; ENSGT00940000158713; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0005021; F:vascular endothelial growth factor receptor activity; IEA:InterPro.
DR GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR042495; PDGFRL.
DR InterPro; IPR009135; VEGFR1_rcpt.
DR PANTHER; PTHR15360:SF2; MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR; 1.
DR PANTHER; PTHR15360; PLATELET-DERIVED GROWTH FACTOR RECEPTOR LIKE; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF21339; VEGFR-1-like_Ig-like; 1.
DR PIRSF; PIRSF000615; TyrPK_CSF1-R; 1.
DR PRINTS; PR01832; VEGFRECEPTOR.
DR PRINTS; PR01833; VEGFRECEPTR1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..541
FT /note="Platelet-derived growth factor receptor-like
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014436876"
FT DOMAIN 32..107
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 230..327
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 349..404
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 428..467
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 541 AA; 60672 MW; AF979461980FBA90 CRC64;
MVSCWDTGVL LCALLGCLLL TGSSSGSKLK GPELSLKGTQ HVMQAGQTLH LQCRGEAAHG
WSLPESVSKE SERLSITKSA CGRNGKQFCS TLTLNAAQAN HTGFYSCKYL PVPISKKKKT
ESAIYIFIND TGRPFVEMYS EIPEIIHMTE GRELIIPCRV TSPNITVTLK KFPLETLIPD
GKRIIWDSRK GFIISNATYK EIGLLTCEAT VNGHLYKTNY LTHRQTNTII DVQISSPPPV
KLLRGHTLIL NCTATTPLNT RVQMTWSYPD EKNKRASVRR RIDQSNSHGN IFYSILTIDK
VQNKDKGLYI CRVRSGPSFK SVNTSVHIYD KAFITVKHRK QQVLETVAGK RSYRLSMKVK
AFPSPEVVWL KDGLPAIEKS ARYLTHGYSL IIKDVTEEDA GNYTILLNIK QSNVFKNLTA
TLIVNVKPQI YEKAVSSFPD PALYPLGSRQ ILTCTAYGIP QPTIKWLWRP CNHSHSEARS
DFCSNNEESF ILDPDSNIGN RIESITQRMA IIEGKNKLPP ANNPFILPPT SFFSNYFHFL
P
//
