ID A0A2K5DFB4_AOTNA Unreviewed; 573 AA.
AC A0A2K5DFB4;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Interleukin 22 receptor subunit alpha 1 {ECO:0000313|Ensembl:ENSANAP00000019653.1};
GN Name=IL22RA1 {ECO:0000313|Ensembl:ENSANAP00000019653.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000019653.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000019653.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_012295676.1; XM_012440253.1.
DR AlphaFoldDB; A0A2K5DFB4; -.
DR STRING; 37293.ENSANAP00000019653; -.
DR Ensembl; ENSANAT00000037526.1; ENSANAP00000019653.1; ENSANAG00000027615.1.
DR GeneID; 105708646; -.
DR CTD; 58985; -.
DR GeneTree; ENSGT00940000161366; -.
DR OMA; WLAKEGC; -.
DR OrthoDB; 5322873at2759; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0042015; F:interleukin-20 binding; IEA:Ensembl.
DR GO; GO:0042018; F:interleukin-22 receptor activity; IEA:Ensembl.
DR GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:Ensembl.
DR GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR PANTHER; PTHR20859:SF20; INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-1; 1.
DR Pfam; PF09294; Interfer-bind; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR PROSITE; PS50853; FN3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..573
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014426619"
FT TRANSMEM 227..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..124
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 404..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 436..458
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 573 AA; 63340 MW; F53329E9195ABD8A CRC64;
MRTLLTILAV GSLAVHAPED FSDLLQNVKF QSSNFENILT WESGPEGTPD TVYSIEYKTY
GEKDWVAKKS CQQITRKSCN LTVETGNFTE LYYARVTAFS AGGRTVTKMT DRFSALQHTT
LKPPDVTCIP KVRSIQMIVH PTPTPIHAGD GHQLTLEEIF QDLSYRLELQ VNHTYQMRLE
GKQREYEFFG LTPDTEFLGT IMVFVTTWFK ESAPYVCRVK TLPDRTWTYS FSGAFLFSMG
FLVAVLCYLS YRYVTKPPAP PNSLNVQRVL TFQPLHFIQE HVLIPVFDLS GPSSLARPVQ
YSQIRVSGPR EPAGAPQRHS LPETTYLGQP DVILQPSNMP PPQIFSPLPY APNTAPEVGP
PSYAPQVTPE AQPPFYTPQA ISKVQPPSYA PQATPDSWPP SYGVCMEGSG KDSPTVTLSS
PKHLRPKGQL QKETPAGSCL PGSLSLQEVT SLAMEESQEA KSLRQPLGVC TDRTSDPDVL
HSGEEGTPQY LKGQLPLLSS VQIEGHPMSL PLHPPSRPCS PSDQGPSPWG LLESLVCPRD
EAKSPAPETA DLEQPTELDA LFRGLALTVQ WEP
//
