ID A0A2K5DLG9_AOTNA Unreviewed; 466 AA.
AC A0A2K5DLG9;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=CTD small phosphatase like 2 {ECO:0000313|Ensembl:ENSANAP00000021722.1};
GN Name=CTDSPL2 {ECO:0000313|Ensembl:ENSANAP00000021722.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000021722.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000021722.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Probable phosphatase. {ECO:0000256|ARBA:ARBA00037324}.
CC -!- SIMILARITY: Belongs to the CTDSPL2 family.
CC {ECO:0000256|ARBA:ARBA00038355}.
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DR RefSeq; XP_012297625.1; XM_012442202.1.
DR RefSeq; XP_012297626.1; XM_012442203.1.
DR AlphaFoldDB; A0A2K5DLG9; -.
DR STRING; 37293.ENSANAP00000021722; -.
DR Ensembl; ENSANAT00000039610.1; ENSANAP00000021722.1; ENSANAG00000028613.1.
DR GeneID; 105710014; -.
DR CTD; 51496; -.
DR GeneTree; ENSGT01040000240503; -.
DR OrthoDB; 5473812at2759; -.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0008420; F:RNA polymerase II CTD heptapeptide repeat phosphatase activity; IEA:Ensembl.
DR GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR GO; GO:0046827; P:positive regulation of protein export from nucleus; IEA:Ensembl.
DR GO; GO:0006611; P:protein export from nucleus; IEA:Ensembl.
DR CDD; cd07521; HAD_FCP1-like; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR011948; Dullard_phosphatase.
DR InterPro; IPR004274; FCP1_dom.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR NCBIfam; TIGR02251; HIF-SF_euk; 1.
DR PANTHER; PTHR12210:SF173; CTD SMALL PHOSPHATASE-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR12210; DULLARD PROTEIN PHOSPHATASE; 1.
DR Pfam; PF03031; NIF; 1.
DR SMART; SM00577; CPDc; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR PROSITE; PS50969; FCP1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT DOMAIN 283..442
FT /note="FCP1 homology"
FT /evidence="ECO:0000259|PROSITE:PS50969"
FT REGION 1..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..78
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 466 AA; 53011 MW; 7A6F7A324326ED27 CRC64;
MRLRTRKASQ QSNQIQTQRT ARAKRKYSEV DDSLPSGGEK PPKNETGLLS SIKKFIKGST
PKEERENPSK RSRIERDIDN NLITSTPRAG EKPNKQISRV RRKSQVNGEA GSYEMTNQHV
KQNGKLEDNP SSGSPPRTTL LGTIFSPVFN FFSPANKNGT SGSDSPGQAV EAEEIVKQLD
MEQVDEITTS TTTSTNGAAY SNQAVQVRAS INNGLEEAEE TVNRDIPPLT VPVTPDSGYS
SAHAEATYEE DWEVFDPYYF IKHVPPLTEE QLNRKPALPL KTRSTPEFSL VLDLDETLVH
CSLNELEDAA LTFPVLFQDV IYQVYVRLRP FFREFLERMS QMYEIILFTA SKKVYADKLL
NILDPKKQLV RHRLFREHCV CVQGNYIKDL NILGRDLSKT IIIDNSPQAF AYQLSNGIPI
ESWFMDKNDN ELLKLIPFLE KLVELNEDVR PHIRDRFRLH DLLPPD
//
