ID A0A2K5DLZ3_AOTNA Unreviewed; 574 AA.
AC A0A2K5DLZ3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=phosphopyruvate hydratase {ECO:0000256|ARBA:ARBA00012058};
DE EC=4.2.1.11 {ECO:0000256|ARBA:ARBA00012058};
DE AltName: Full=2-phospho-D-glycerate hydro-lyase {ECO:0000256|ARBA:ARBA00031125};
GN Name=ENO4 {ECO:0000313|Ensembl:ENSANAP00000021996.1};
OS Aotus nancymaae (Ma's night monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC Aotus.
OX NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000021996.1, ECO:0000313|Proteomes:UP000233020};
RN [1] {ECO:0000313|Ensembl:ENSANAP00000021996.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-
CC glyceraldehyde 3-phosphate: step 4/5. {ECO:0000256|ARBA:ARBA00005031}.
CC -!- SIMILARITY: Belongs to the enolase family.
CC {ECO:0000256|ARBA:ARBA00009604}.
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DR RefSeq; XP_012303461.1; XM_012448038.1.
DR AlphaFoldDB; A0A2K5DLZ3; -.
DR Ensembl; ENSANAT00000039888.1; ENSANAP00000021996.1; ENSANAG00000028750.1.
DR GeneID; 105714145; -.
DR CTD; 387712; -.
DR GeneTree; ENSGT00950000182805; -.
DR OrthoDB; 2908712at2759; -.
DR UniPathway; UPA00109; UER00187.
DR Proteomes; UP000233020; Unplaced.
DR GO; GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004634; F:phosphopyruvate hydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR000941; Enolase.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR020810; Enolase_C.
DR InterPro; IPR020811; Enolase_N.
DR PANTHER; PTHR11902; ENOLASE; 1.
DR PANTHER; PTHR11902:SF30; ENOLASE 4; 1.
DR Pfam; PF00113; Enolase_C; 1.
DR SMART; SM01192; Enolase_C; 1.
DR SMART; SM01193; Enolase_N; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT DOMAIN 14..207
FT /note="Enolase N-terminal"
FT /evidence="ECO:0000259|SMART:SM01193"
FT DOMAIN 219..524
FT /note="Enolase C-terminal TIM barrel"
FT /evidence="ECO:0000259|SMART:SM01192"
FT REGION 134..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..152
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 574 AA; 62614 MW; CFEFA7DA3029AA9E CRC64;
MANCFSKLAK PPTICKIVGK DVLDGLGLPT LQVEIFCTIQ NFPKSICSVV ISTHFEVHEN
ALPELAEVEE AERASAVSTA VQWVNGSITH ELQGIPPFDQ AEVDHLLRKF FASKVQEDKE
RKKLEKSLEY STVLIPLPPV PPPPPPPPPT KKKGQKPGRK DTATEKTITP AEPVEPVLSG
SMAIGAVSLA VAKTCGMLLN NPLYLNIALL KHNQEQPTML SMPLLMVSLV SCGKSSSGKL
NLMKEVICIP HPELTTKQGI EMLMEIQKHI NKIIEMPSPP KAETKKGHDG SKRGQQQITG
KMSHLGCLTI SCNTIEQPLV LIQGICANLG LELGTNLHLA INCAGHELMD YSKGKYEVMM
GTYKNAAEMV DLYVDLINKY PSIIALIDPF RKEDFKQWDS IYHALGSRCY IIAGTASKSI
SKLLEQGNIG IPKSNGLIIK HTNQTTMSDL VEITNLIDSK KHIAVFGSTE GESSDDSLVD
LAVGLGVRFI KLGGLSRGER VTKYNRLLTI EEELVQNGTL GFNEEHTFFY CNEEAEKTAE
ALEAAAAGEL LEPLEPTFLT QGVEESAETR ASSG
//
