ID   A0A2K5DRD9_AOTNA        Unreviewed;      1038 AA.
AC   A0A2K5DRD9;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=GTPase activating Rap/RanGAP domain like 3 {ECO:0000313|Ensembl:ENSANAP00000023513.1};
GN   Name=GARNL3 {ECO:0000313|Ensembl:ENSANAP00000023513.1};
OS   Aotus nancymaae (Ma's night monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae;
OC   Aotus.
OX   NCBI_TaxID=37293 {ECO:0000313|Ensembl:ENSANAP00000023513.1, ECO:0000313|Proteomes:UP000233020};
RN   [1] {ECO:0000313|Ensembl:ENSANAP00000023513.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_012313536.1; XM_012458113.1.
DR   AlphaFoldDB; A0A2K5DRD9; -.
DR   STRING; 37293.ENSANAP00000023513; -.
DR   Ensembl; ENSANAT00000041423.1; ENSANAP00000023513.1; ENSANAG00000029515.1.
DR   GeneID; 105721185; -.
DR   CTD; 84253; -.
DR   GeneTree; ENSGT00940000159362; -.
DR   OrthoDB; 25782at2759; -.
DR   Proteomes; UP000233020; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   PANTHER; PTHR15711:SF62; GTPASE-ACTIVATING RAP_RAN-GAP DOMAIN-LIKE PROTEIN 3; 1.
DR   PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR   Pfam; PF00780; CNH; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   SMART; SM00036; CNH; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50219; CNH; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468, ECO:0000256|PROSITE-
KW   ProRule:PRU00165}; Reference proteome {ECO:0000313|Proteomes:UP000233020}.
FT   DOMAIN          214..430
FT                   /note="Rap-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50085"
FT   DOMAIN          512..823
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
FT   REGION          833..865
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          936..1038
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        833..852
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        936..965
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        970..992
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        993..1008
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1038 AA;  115610 MW;  C80DDFFC09AA3066 CRC64;
     MDPLTKGPCG SQMAQTLLWK AKSSLSFGIQ PLQTWPTKEP ELESQVNLSV SEDLGCRRGD
     FSRKHYGSVE LLISSDADGA IQRAGRFRVE NGSSDENATA LPGTWRRTDV HLENPEYHTR
     WYFKYFLGQV HQNYIGNDAE KSPFFLSVTL SDQNNQRVPQ YRAILWRKTG TQKICLPYSP
     TKTLSVKSIL SAMNLDKFEK GPREIFHPEI QKDLLVLEEQ EGSVNFKFGV LFAKDGQLTD
     DEMFSNEIGS EAFQKFLNLL GDTITLKGWT GYRGGLDTKN DTTGIHSVYT VYQGHEIMFH
     VSTMLPYSKE NKQQVERKRH IGNDIVTIVF QEGEESSPAF KPSMIRSHFT HIFALVRYDQ
     ENDNYRLKIF SEESVPLFGP PLPTPPVFTD HQEFRDFLLV KLINGEKATL ETPTFAQKRR
     RTLDMLIRSL HQDLMPDLHK NMLNRRSFSD VLPESPKSAR KKEEARQAEF VRIGQALKLK
     SIVRGDAPSS LAASGICKKE PWEPQCFCSN FPHEAVCADP WGQALLVSTD AGVLLVDDDL
     PSVPVFDRTL PVKQMHVLEI LDLLVLRADK GKDARLFVFR LSALQKGLEG KQAGKSRSDC
     RENKLEKTKG CHLYAVNTHH SRELRIVVAI RNKLLLITRK HNKPSGVTST SLLSPLVESP
     VEEFQYIREI CLSDSPVVMT LVDGPTEESD NLICVAYRHQ FDVVNESTGE AFRLHHVEAN
     RVNFVAAIDV YEDGEAGLLL CYNYSCIYKK VCPFNGGSFL VQPSASDFQF CWNQAPYAIV
     CAFPYLLAFT TDSMEIRLVV NGNLVHTAIV PQLQLVASRS DIYFTATAAV NEVSSGGSSK
     GASARNSPQT PPGRDTPVFP SSLGEGEIQS KNLYKIPLRN LVGRSIERPL KSPLVSKVIT
     PPTPISVGLA AIPVTHSLSL SRMEIKEIAS RTRRELLGLS DEGGPKSEGM PKAKSKPRKR
     LEESQGGPKP GAVRSSSSDR IPSGSLESAS TSEANPEEHH HSASSDQDPV ADREGSPVSG
     SSPFQLTAFS DEDIIDLK
//